Localization of integral membrane peptidylglycine alpha-amidating monooxygenase in neuroendocrine cells

Peptidylglycine alpha-amidating monooxygenase (PAM) catalyzes the amidation of glycine-extended peptides in neuroendocrine cells. At steady state, membrane PAM is accumulated in a perinuclear compartment. We examined the distribution of membrane PAM in stably transfected AtT-20 cells and compared it...

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Veröffentlicht in:	Journal of cell science 1997-03, Vol.110 ( Pt 6) (6), p.695-706
Hauptverfasser:	Milgram, S L, Kho, S T, Martin, G V, Mains, R E, Eipper, B A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex - cytology Adrenal Cortex - enzymology Cell Compartmentation Cell Line Endocytosis Microscopy, Fluorescence Microscopy, Immunoelectron Mixed Function Oxygenases - metabolism Multienzyme Complexes
Online-Zugang:	Volltext
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