Correlation between enzyme activity and hinge‐bending domain displacement in 3‐phosphoglycerate kinase

Diffuse X‐ray‐scattering data give evidence for large‐scale structural change in pig muscle 3‐phosphoglycerate kinase upon substrate binding. Simultaneous binding of 3‐phosphoglycerate and MgATP either to the unmodified enzyme or to its active methylated derivative leads to about an 0.1‐nm decrease...

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