Ginkgo biloba extract (egb 761): inhibitory effect on nitric oxide production in the macrophage cell line raw 264.7

The present study was conducted to evaluate the effect of Ginkgo biloba extract (EGb 761) on the synthesis of nitric oxide (NO) induced by lipopolysaccharide (LPS) plus interferon-γ (IFN-γ) in the mouse macrophage cell line RAW 264.7. EGb 761 inhibited nitrite and nitrate production, taken as an ind...

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Veröffentlicht in:	Biochemical pharmacology 1997-03, Vol.53 (6), p.897-903
Hauptverfasser:	Kobuchi, Hirotsugu, Therese Droy-lefaix, Marie, Christen, Yves, Packer, Lester
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Line DNA - metabolism EGb 761 flavonoids Free Radical Scavengers - pharmacology General pharmacology Ginkgo biloba Ginkgo biloba extract inducible nitric oxide synthase macrophages Macrophages - metabolism Medical sciences Mice NF-kappa B - metabolism Nitrates - metabolism nitric oxide Nitric Oxide - biosynthesis Nitric Oxide Synthase - antagonists & inhibitors Nitric Oxide Synthase - genetics Nitrites - metabolism Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - pharmacology RNA, Messenger - analysis
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