Mutual contact of murine erythroleukemia cells activates depolarizing cation channels, whereas contact with extracellular substrata activates hyperpolarizing Ca2+-dependent K+ channels

This study deals with the modulation of the plasma membrane potential (Δψp) of murine erythroleukemia (MEL) cells by cell‐substratum or cell‐cell contact. Δψp was determined by measuring the distribution of tetraphenylphosphonium (TPP+) across the plasma membrane; it appeared strongly, and inversely...

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Veröffentlicht in:	Journal of cellular physiology 1989-04, Vol.139 (1), p.1-8
Hauptverfasser:	Arcangeli, Annarosa, Del Bene, Maria Riccarda, Poli, Riccardo, Ricupero, Letizia, Olivotto, Massimo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biomechanical Phenomena Calcimycin - pharmacology Calcium - physiology Cations - metabolism Cell Communication Cell interactions, adhesion Cell Membrane - physiology Cells, Cultured Electrophysiology Extracellular Space - physiology Fundamental and applied biological sciences. Psychology Ion Channels - physiology Ions Leukemia, Erythroblastic, Acute - metabolism Leukemia, Erythroblastic, Acute - pathology Leukemia, Erythroblastic, Acute - physiopathology Mice Molecular and cellular biology Potassium Channels - physiology Sodium - physiology Valinomycin - pharmacology
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