Value of Cytomegalovirus (CMV) IgG Avidity Index for the Diagnosis of Primary CMV Infection in Pregnant Women

This study assessed the diagnostic value of the cytomegalovirus (CMV)-specific IgGavidity index (AI) for pregnant women without a history of CMV seroconversion. Sera were studied from 40 women with CMV seroconversion (group I), 70 with past CMV infection (group II), 10 (20 sera) with serologic react...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of infectious diseases 1997-04, Vol.175 (4), p.944-946
Hauptverfasser:	Grangeot-Keros, Liliane, Mayaux, Marie Jeanne, Lebon, Pierre, Freymuth, François, Eugene, Geneviève, Stricker, René, Dussaix, Elisabeth
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibodies, Viral - blood Antibody Affinity Assessed values Biological and medical sciences Concise Communications Cytomegalovirus Cytomegalovirus - immunology Cytomegalovirus Infections - diagnosis Diagnostic indices Female Herpesviridae Human viral diseases Humans Immunoglobulin G - blood Infant, Newborn Infants Infections Infectious diseases Medical sciences Miscellaneous Pregnancy Pregnancy Complications, Infectious - diagnosis Rubella Viral diseases Women
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	This study assessed the diagnostic value of the cytomegalovirus (CMV)-specific IgGavidity index (AI) for pregnant women without a history of CMV seroconversion. Sera were studied from 40 women with CMV seroconversion (group I), 70 with past CMV infection (group II), 10 (20 sera) with serologic reactivation (group III), and 41 with CMV-specific IgMwithout proven seroconversion (group IV). Sera from women in group I collected 60% (mean, 88% ± 9%). Among the 41 babies born to group IV women, only 4 were infected with CMV (all born to mothers with a low [
ISSN:	0022-1899 1537-6613
DOI:	10.1086/513996