Isolation and Characterization of the Human Parathyroid Hormone-Like Peptide Gene

A parathyroid hormone-like peptide (PTHLP) has recently been identified in human tumors associated with the syndrome of humoral hypercalcemia of malignancy. The peptide appears to be encoded by a single-copy gene that gives rise to multiple mRNAs that are heterogeneous at both their 5′ and their 3′...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1989-04, Vol.86 (7), p.2408-2412
Hauptverfasser:	Mangin, Marguerite, Ikeda, Kyoji, Dreyer, Barbara E., Broadus, Arthur E.
Format:	Artikel
Sprache:	eng
Schlagworte:	550401 - Genetics- Tracer Techniques Amino Acid Sequence Amino acids ANIMAL CELLS Base Sequence BASIC BIOLOGICAL SCIENCES BETA DECAY RADIOISOTOPES BETA-MINUS DECAY RADIOISOTOPES Biological and medical sciences CHROMOSOMES Cloning, Molecular Codon - genetics Complementary DNA CONNECTIVE TISSUE CELLS DAYS LIVING RADIOISOTOPES DISEASES DNA DNA HYBRIDIZATION DNA, Neoplasm - genetics DNA, Neoplasm - isolation & purification Exons FIBROBLASTS Fundamental and applied biological sciences. Psychology GENES Genes. Genome GENETIC MAPPING HETEROCHROMOSOMES HORMONES Humans HYBRIDIZATION Introns ISOTOPES LIGHT NUCLEI MAPPING MESSENGER-RNA Molecular and cellular biology Molecular genetics Molecular Sequence Data MOLECULAR STRUCTURE Neoplasm Proteins - genetics NEOPLASMS NUCLEI Nucleic Acid Hybridization NUCLEIC ACIDS Nucleotides ODD-ODD NUCLEI ORGANIC COMPOUNDS PARATHORMONE Parathyroid Hormone - genetics Parathyroid Hormone-Related Protein PEPTIDE HORMONES PHOSPHORUS 32 PHOSPHORUS ISOTOPES RADIOISOTOPES Restriction Mapping RNA SOMATIC CELLS Splicing Squamous cell carcinoma Tumors Untranslated regions
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