Murine Models of Chlamydia pneumoniae Infection and Atherosclerosis

Chlamydia pneumoniae have been demonstrated in atherosclerotic lesions but not in normal arteries. An animal model of both C. pneumoniae and atherosclerosis is needed to investigate the role of the organism in atherosclerosis. Apolipoprotein (apo) E-deficient transgenic mice, which spontaneously dev...

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Veröffentlicht in:	The Journal of infectious diseases 1997-04, Vol.175 (4), p.883-890
Hauptverfasser:	Moazed, Teresa C., Kuo, Cho-chou, Grayston, J. Thomas, Campbell, Lee Ann
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Bacterial - blood Antigens Aorta Apolipoproteins E - deficiency Arteriosclerosis - etiology Atherosclerosis Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Chlamydia Infections - complications Chlamydia Infections - immunology Chlamydia Infections - pathology Chlamydia pneumoniae Chlamydophila pneumoniae Disease Models, Animal DNA, Bacterial - analysis Immunohistochemistry Infections Inoculation Isols Lesions Lungs Major Articles Male Medical sciences Mice Mice, Inbred C57BL Polymerase Chain Reaction
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