In vivo characterization of phencyclidine/σ agonist-mediated inhibition of nociception

Substance P and excitatory amino acids have been implicated as potential nociceptive neurotransmitters in several investigations. Excitatory amino acids acting at N-methyl-D-aspartate (NMDA) receptors are of particular interest because of the description of NMDA/phencyclidine (PCP) receptor complexe...

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Veröffentlicht in:	European journal of pharmacology 1989-01, Vol.159 (2), p.149-156
Hauptverfasser:	DeLander, Gary E., Wahl, Jeffrey J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics Animals Anticonvulsants - pharmacology Antinociception Aspartic Acid - analogs & derivatives Aspartic Acid - antagonists & inhibitors Behavior, Animal - drug effects Binding, Competitive - drug effects Biological and medical sciences Dibenzocycloheptenes - pharmacology Dizocilpine Maleate Excitatory amino acids Male Medical sciences Mice N-Methylaspartate Neuropharmacology Nociceptors - drug effects Pharmacology. Drug treatments Phenazocine - analogs & derivatives Phenazocine - pharmacology Phencyclidine - pharmacology Phencyclidine receptors Receptors, Opioid - physiology Receptors, Opioid, delta Substance P Substance P - antagonists & inhibitors
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