Nicotinic acetylcholine receptor (nACh-R) agonist-induced changes in brain monoamine turnover in mice

The aim of the present study was to evaluate the effects of nicotinic acetylcholine receptor (nACh-R) agonists such as (-)-nicotine and related compounds on brain monoamine turnover. A single administration of (-)-nicotine (0.04, 0.2, 1.0, and 5.0 mg/kg SC) increased both noradrenaline (NA) and dopa...

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Veröffentlicht in:	Psychopharmacologia 1997-02, Vol.129 (3), p.225-232
Hauptverfasser:	TANI, Y, SAITO, K, TSUNEYOSHI, A, IMOTO, M, OHNO, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase Agonists Alkaloids - pharmacology Animals Azocines Binding, Competitive Biological and medical sciences Brain - drug effects Brain - metabolism Cholinergic system Dopamine - metabolism Isoxazoles - pharmacology Lobeline Male Mecamylamine Mecamylamine - pharmacology Medical sciences Mice Mice, Inbred Strains Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Nicotine Nicotine - metabolism Nicotine - pharmacology Nicotinic Agonists - pharmacology Nicotinic Antagonists - pharmacology Norepinephrine Norepinephrine - metabolism Pharmacology. Drug treatments Pyrrolidines - pharmacology Quinolizines Serotonin Serotonin - metabolism Tacrine - pharmacology
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