Evidence for Thiol-Dependent Production of Oxygen Radicals by 4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione (Oltipraz) and 3H-1,2-Dithiole-3-thione:  Possible Relevance to the Anticarcinogenic Properties of 1,2-Dithiole-3-thiones

1,2-Dithiole-3-thiones are an important class of anticarcinogens that selectively induce cellular production of chemoprotective phase II detoxification enzymes. It is important to identify chemical properties of anticarcinogens that are responsible for this enzyme induction. Previously, the ability...

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Veröffentlicht in:Chemical research in toxicology 1997-03, Vol.10 (3), p.296-301
Hauptverfasser: Kim, Woongki, Gates, Kent S
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Sprache:eng
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