Acquired von Willebrand's disease due to aberrant expression of platelet glycoprotein Ib by marginal zone lymphoma cells

A 69‐year‐old woman presented with splenic marginal zone lymphoma associated with acquired von Willebrand's disease (AVWD). Laboratory abnormalities included markedly decreased plasma levels of factor VIII coagulant (C) activity (VIII:C 28%), von Willebrand’s factor (VWF) antigen (Ag) (vWF:Ag ...

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Veröffentlicht in:	British journal of haematology 1997-03, Vol.96 (4), p.850-853
Hauptverfasser:	TEFFERI, AYALEW, HANSON, CURTIS A., KURTIN, PAUL J., KATZMANN, JERRY A., DALTON, ROBERT J., NICHOLS, WILLIAM L.
Format:	Artikel
Sprache:	eng
Schlagworte:	acquired von Willebrand's disease Aged Antigens, Human Platelet - analysis Biological and medical sciences Female Flow Cytometry glycoprotein Ib Hematologic and hematopoietic diseases Humans Immunophenotyping Leukemia, Lymphocytic, Chronic, B-Cell - metabolism lymphoma Lymphoma, B-Cell - blood Lymphoma, B-Cell - complications Lymphoma, B-Cell - surgery Medical sciences Platelet diseases and coagulopathies Platelet Glycoprotein GPIb-IX Complex - metabolism Splenectomy Splenic Neoplasms - blood Splenic Neoplasms - complications Splenic Neoplasms - surgery von Willebrand Diseases - blood von Willebrand Diseases - etiology
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Zusammenfassung:	A 69‐year‐old woman presented with splenic marginal zone lymphoma associated with acquired von Willebrand's disease (AVWD). Laboratory abnormalities included markedly decreased plasma levels of factor VIII coagulant (C) activity (VIII:C 28%), von Willebrand’s factor (VWF) antigen (Ag) (vWF:Ag
ISSN:	0007-1048 1365-2141
DOI:	10.1046/j.1365-2141.1997.d01-2088.x