Community-acquired pneumonia in the elderly: Association of mortality with lack of fever and leukocytosis
Elderly patients with community-acquired pneumonia may not have a systemic inflammatory response characterized by fever and leukocytosis. We compared lack of fever and leukocytosis with mortality in elderly patients with community-acquired pneumonia. Patients with fever and leukocytosis (group A, 47...
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| Veröffentlicht in: | Southern medical journal (Birmingham, Ala.) Ala.), 1997-03, Vol.90 (3), p.296-298 |
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| container_title | Southern medical journal (Birmingham, Ala.) |
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| creator | AHKEE, S SRINATH, L RAMIREZ, J |
| description | Elderly patients with community-acquired pneumonia may not have a systemic inflammatory response characterized by fever and leukocytosis. We compared lack of fever and leukocytosis with mortality in elderly patients with community-acquired pneumonia. Patients with fever and leukocytosis (group A, 47 patients) were compared with those without fever and leukocytosis (group B, 17 patients). Comparison of the two groups by unpaired, two-tailed t test showed that lack of fever and leukocytosis correlated with mortality. Hospitalized elderly patients who have community-acquired pneumonia without fever and leukocytosis are seven times more likely to die than those who have these symptoms. Future research in the adjunct use of immune modulators such as granulocyte colony-stimulating factor in these patients should be encouraged. |
| doi_str_mv | 10.1097/00007611-199703000-00006 |
| format | Article |
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We compared lack of fever and leukocytosis with mortality in elderly patients with community-acquired pneumonia. Patients with fever and leukocytosis (group A, 47 patients) were compared with those without fever and leukocytosis (group B, 17 patients). Comparison of the two groups by unpaired, two-tailed t test showed that lack of fever and leukocytosis correlated with mortality. Hospitalized elderly patients who have community-acquired pneumonia without fever and leukocytosis are seven times more likely to die than those who have these symptoms. 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We compared lack of fever and leukocytosis with mortality in elderly patients with community-acquired pneumonia. Patients with fever and leukocytosis (group A, 47 patients) were compared with those without fever and leukocytosis (group B, 17 patients). Comparison of the two groups by unpaired, two-tailed t test showed that lack of fever and leukocytosis correlated with mortality. Hospitalized elderly patients who have community-acquired pneumonia without fever and leukocytosis are seven times more likely to die than those who have these symptoms. 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SRINATH, L ; RAMIREZ, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c339t-fd43ed5be4574c461079e8892f19e0d8e5fc0e1396048776ea23a50a3f4dc79f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adjuvants, Immunologic - therapeutic use</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Alcohol Drinking - epidemiology</topic><topic>Bacteremia - immunology</topic><topic>Bacteremia - physiopathology</topic><topic>Bacterial diseases</topic><topic>Bacterial diseases of the respiratory system</topic><topic>Biological and medical sciences</topic><topic>Community-Acquired Infections - immunology</topic><topic>Community-Acquired Infections - mortality</topic><topic>Community-Acquired Infections - physiopathology</topic><topic>Community-Acquired Infections - therapy</topic><topic>Fever - immunology</topic><topic>Fever - physiopathology</topic><topic>Granulocyte Colony-Stimulating Factor - therapeutic use</topic><topic>Heart Failure - epidemiology</topic><topic>Hospitalization</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Kentucky - epidemiology</topic><topic>Leukocytosis - immunology</topic><topic>Leukocytosis - physiopathology</topic><topic>Lung Diseases, Obstructive - epidemiology</topic><topic>Medical sciences</topic><topic>Pneumonia, Bacterial - immunology</topic><topic>Pneumonia, Bacterial - mortality</topic><topic>Pneumonia, Bacterial - physiopathology</topic><topic>Pneumonia, Bacterial - therapy</topic><topic>Prospective Studies</topic><topic>Respiratory Insufficiency - epidemiology</topic><topic>Smoking - epidemiology</topic><topic>Survival Rate</topic><topic>Systemic Inflammatory Response Syndrome - immunology</topic><topic>Systemic Inflammatory Response Syndrome - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>AHKEE, S</creatorcontrib><creatorcontrib>SRINATH, L</creatorcontrib><creatorcontrib>RAMIREZ, J</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Southern medical journal (Birmingham, Ala.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>AHKEE, S</au><au>SRINATH, L</au><au>RAMIREZ, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Community-acquired pneumonia in the elderly: Association of mortality with lack of fever and leukocytosis</atitle><jtitle>Southern medical journal (Birmingham, Ala.)</jtitle><addtitle>South Med J</addtitle><date>1997-03-01</date><risdate>1997</risdate><volume>90</volume><issue>3</issue><spage>296</spage><epage>298</epage><pages>296-298</pages><issn>0038-4348</issn><eissn>1541-8243</eissn><abstract>Elderly patients with community-acquired pneumonia may not have a systemic inflammatory response characterized by fever and leukocytosis. We compared lack of fever and leukocytosis with mortality in elderly patients with community-acquired pneumonia. Patients with fever and leukocytosis (group A, 47 patients) were compared with those without fever and leukocytosis (group B, 17 patients). Comparison of the two groups by unpaired, two-tailed t test showed that lack of fever and leukocytosis correlated with mortality. Hospitalized elderly patients who have community-acquired pneumonia without fever and leukocytosis are seven times more likely to die than those who have these symptoms. Future research in the adjunct use of immune modulators such as granulocyte colony-stimulating factor in these patients should be encouraged.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>9076300</pmid><doi>10.1097/00007611-199703000-00006</doi><tpages>3</tpages></addata></record> |
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| identifier | ISSN: 0038-4348 |
| ispartof | Southern medical journal (Birmingham, Ala.), 1997-03, Vol.90 (3), p.296-298 |
| issn | 0038-4348 1541-8243 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adjuvants, Immunologic - therapeutic use Age Factors Aged Alcohol Drinking - epidemiology Bacteremia - immunology Bacteremia - physiopathology Bacterial diseases Bacterial diseases of the respiratory system Biological and medical sciences Community-Acquired Infections - immunology Community-Acquired Infections - mortality Community-Acquired Infections - physiopathology Community-Acquired Infections - therapy Fever - immunology Fever - physiopathology Granulocyte Colony-Stimulating Factor - therapeutic use Heart Failure - epidemiology Hospitalization Human bacterial diseases Humans Infectious diseases Kentucky - epidemiology Leukocytosis - immunology Leukocytosis - physiopathology Lung Diseases, Obstructive - epidemiology Medical sciences Pneumonia, Bacterial - immunology Pneumonia, Bacterial - mortality Pneumonia, Bacterial - physiopathology Pneumonia, Bacterial - therapy Prospective Studies Respiratory Insufficiency - epidemiology Smoking - epidemiology Survival Rate Systemic Inflammatory Response Syndrome - immunology Systemic Inflammatory Response Syndrome - physiopathology |
| title | Community-acquired pneumonia in the elderly: Association of mortality with lack of fever and leukocytosis |
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