Inhibition of guinea pig lordosis behavior by the phenylethanolamine N-methyltransferase (PNMT) inhibitor SKF-64139: Mediation by α noradrenergic receptors

Experiments were undertaken to determine whether the steroid-dependent lordosis response of female guinea pigs is under adrenergic control. In initial experiments, treatment with the centrally active phenylethanolomine N-methyltransferase (PNMT; the enzyme catalyzing methylation of norepinephrine to...

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Veröffentlicht in:	Hormones and behavior 1989-03, Vol.23 (1), p.106-117
Hauptverfasser:	Feder, Harvey H, Crowley, William R, Nock, Bruce
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavioral psychophysiology Biological and medical sciences Brain - drug effects Clonidine - pharmacology Cricetinae Dose-Response Relationship, Drug Estradiol - pharmacology Female Fundamental and applied biological sciences. Psychology Isoquinolines - pharmacology Monoamine Oxidase Inhibitors - pharmacology Neurotransmission and behavior Ovariectomy Phenylethanolamine N-Methyltransferase - antagonists & inhibitors Progesterone - pharmacology Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Receptors, Adrenergic - drug effects Sexual Behavior, Animal - drug effects Spinal Cord - drug effects Tetrahydroisoquinolines
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