Tear film stability of protein extracts from dry eye patients administered a sigma agonist

Fourteen dry eye volunteers placed one to two drops of 0.15% AF2975 (N,N-dimethyl-2-phenylethylamine HCl) in one eye and the vehicle in their other eye four times a day for 21 days. AF2975 is a sigma agonist known to stimulate the release of tear proteins after instillation in rabbit eyes and was te...

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Veröffentlicht in:	Journal of ocular pharmacology and therapeutics 1997-04, Vol.13 (2), p.151-161
Hauptverfasser:	SCHOENWALD, R. D, VIDVAUNS, S, WURSTER, D. E, BARFKNECHT, C. F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Carrier Proteins - analysis Chromatography, High Pressure Liquid Eye Female Humans Lipocalin 1 Male Medical sciences Middle Aged Pharmacology. Drug treatments Phenethylamines - pharmacology Proteins - analysis Receptors, sigma - agonists Receptors, sigma - drug effects Receptors, sigma - metabolism Surface Tension Tears - chemistry Xerophthalmia - metabolism Xerophthalmia - physiopathology
Online-Zugang:	Volltext
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