Enhancement of the antiallodynic and antinociceptive efficacy of spinal morphine by antisera to dynorphin A (1–13) or MK-801 in a nerve-ligation model of peripheral neuropathy

Neuropathic pains arising from peripheral nerve injury can result in increased sensitivity to both noxious and non-noxious stimuli and are accompanied by a number of neuroplastic alterations at the level of the spinal cord including upregulation of neurotransmitters including dynorphin, cholecystoki...

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Veröffentlicht in:Pain (Amsterdam) 1997-02, Vol.69 (3), p.317-322
Hauptverfasser: Nichols, Michael L, Lopez, Yvan, Ossipov, Michael H, Bian, Di, Porreca, Frank
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Sprache:eng
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