New endoscopic treatment for chronic pancreatitis, using contrast media containing ulinastatin and prednisolone
The preventive effects of contrast media containing ulinastatin (UST) and/or prednisolone (PDN) on potential complications associated with endoscopic retrograde cholangiopancreatography (ERCP) were studied in 111 patients. The incidence of abdominal pain and the elevation in the serum amylase level...
Gespeichert in:
| Veröffentlicht in: | Journal of gastroenterology 1997-04, Vol.32 (2), p.216-221 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 221 |
|---|---|
| container_issue | 2 |
| container_start_page | 216 |
| container_title | Journal of gastroenterology |
| container_volume | 32 |
| creator | Ohwada, M Watanabe, N Maeda, M Gotoh, M Teramoto, J Moriya, H Nakajima, T Okamoto, T Tsuji, N Kobayashi, D Niitsu, Y |
| description | The preventive effects of contrast media containing ulinastatin (UST) and/or prednisolone (PDN) on potential complications associated with endoscopic retrograde cholangiopancreatography (ERCP) were studied in 111 patients. The incidence of abdominal pain and the elevation in the serum amylase level after ERCP were lower in the UST group than in the control group and abdominal pain and the elevated serum amylase level were almost completely suppressed in the PDN and UST/PDN groups. Based on these findings, a comparative study was conducted to evaluate the effectiveness of a combination of UST and PDN, given via the pancreatic duct, in alleviating pain symptoms in 57 patients with chronic pancreatitis and abdominal pain. The post-ERCP serum amylase level in some patients in the PDN and UST/PDN groups was lower than the pretreatment value. After ERCP, the abdominal pain that had been experienced before ERCP was relieved, and the value of the bentiromide-paraaminobenzoic acid (BT-PABA) test had improved. These results suggest that the use of contrast media containing PDN or UST/PDN in patients with chronic pancreatitis is extremely effective not only for preventing potential complications related to ERCP but also as a new diagnostic treatment method. |
| doi_str_mv | 10.1007/bf02936371 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_78896819</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2787045703</sourcerecordid><originalsourceid>FETCH-LOGICAL-c405t-29dc0c3b244814af10f1e1c47d34f7eed78bed9caeadb0bca5d8bff574a07be23</originalsourceid><addsrcrecordid>eNpdkc1LxDAQxYMoun5cvAsBwYNYnTSpSY8qrgqiFz2XNJlopJvUpEX87-3q6sHTMPN-PIb3CNlncMoA5FnroKz5OZdsjcyY4FVR1WW5TmZQC1EwJsUW2c75DYBxqNQm2axBVUyyGYkP-EEx2JhN7L2hQ0I9LDAM1MVEzWuKYbr2Opil4AefT-iYfXihJoYh6TzQBVqvv1ftw1IZOx8mYcID1cHSPqENPscuBtwlG053GfdWc4c8z6-frm6L-8ebu6uL-8IIqIairK0Bw9tSCMWEdgwcQ2aEtFw4iWilatHWRqO2LbRGV1a1zlVSaJAtlnyHHP349im-j5iHZuGzwa7TAeOYG6lUfa5YPYGH_8C3OKYw_daUUkkQlQQ-Ucc_lEkx54Su6ZNf6PTZMGiWHTSX898OJvhgZTm2Uzh_6Cp0_gXv1oRW</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2787045703</pqid></control><display><type>article</type><title>New endoscopic treatment for chronic pancreatitis, using contrast media containing ulinastatin and prednisolone</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Ohwada, M ; Watanabe, N ; Maeda, M ; Gotoh, M ; Teramoto, J ; Moriya, H ; Nakajima, T ; Okamoto, T ; Tsuji, N ; Kobayashi, D ; Niitsu, Y</creator><creatorcontrib>Ohwada, M ; Watanabe, N ; Maeda, M ; Gotoh, M ; Teramoto, J ; Moriya, H ; Nakajima, T ; Okamoto, T ; Tsuji, N ; Kobayashi, D ; Niitsu, Y</creatorcontrib><description>The preventive effects of contrast media containing ulinastatin (UST) and/or prednisolone (PDN) on potential complications associated with endoscopic retrograde cholangiopancreatography (ERCP) were studied in 111 patients. The incidence of abdominal pain and the elevation in the serum amylase level after ERCP were lower in the UST group than in the control group and abdominal pain and the elevated serum amylase level were almost completely suppressed in the PDN and UST/PDN groups. Based on these findings, a comparative study was conducted to evaluate the effectiveness of a combination of UST and PDN, given via the pancreatic duct, in alleviating pain symptoms in 57 patients with chronic pancreatitis and abdominal pain. The post-ERCP serum amylase level in some patients in the PDN and UST/PDN groups was lower than the pretreatment value. After ERCP, the abdominal pain that had been experienced before ERCP was relieved, and the value of the bentiromide-paraaminobenzoic acid (BT-PABA) test had improved. These results suggest that the use of contrast media containing PDN or UST/PDN in patients with chronic pancreatitis is extremely effective not only for preventing potential complications related to ERCP but also as a new diagnostic treatment method.</description><identifier>ISSN: 0944-1174</identifier><identifier>EISSN: 1435-5922</identifier><identifier>DOI: 10.1007/bf02936371</identifier><identifier>PMID: 9085171</identifier><language>eng</language><publisher>Japan: Springer Nature B.V</publisher><subject>Abdomen ; Abdominal Pain - epidemiology ; Abdominal Pain - prevention & control ; Aged ; Amylases - blood ; Cholangiopancreatography, Endoscopic Retrograde - adverse effects ; Chronic Disease ; Contrast agents ; Contrast Media ; Endoscopy ; Female ; Glucocorticoids ; Glycoproteins ; Humans ; Incidence ; Male ; Middle Aged ; Pain ; Pancreatitis ; Pancreatitis - diagnostic imaging ; Pancreatitis - prevention & control ; Prednisolone ; Trypsin Inhibitors</subject><ispartof>Journal of gastroenterology, 1997-04, Vol.32 (2), p.216-221</ispartof><rights>Springer-Verlag 1997.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c405t-29dc0c3b244814af10f1e1c47d34f7eed78bed9caeadb0bca5d8bff574a07be23</citedby><cites>FETCH-LOGICAL-c405t-29dc0c3b244814af10f1e1c47d34f7eed78bed9caeadb0bca5d8bff574a07be23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9085171$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ohwada, M</creatorcontrib><creatorcontrib>Watanabe, N</creatorcontrib><creatorcontrib>Maeda, M</creatorcontrib><creatorcontrib>Gotoh, M</creatorcontrib><creatorcontrib>Teramoto, J</creatorcontrib><creatorcontrib>Moriya, H</creatorcontrib><creatorcontrib>Nakajima, T</creatorcontrib><creatorcontrib>Okamoto, T</creatorcontrib><creatorcontrib>Tsuji, N</creatorcontrib><creatorcontrib>Kobayashi, D</creatorcontrib><creatorcontrib>Niitsu, Y</creatorcontrib><title>New endoscopic treatment for chronic pancreatitis, using contrast media containing ulinastatin and prednisolone</title><title>Journal of gastroenterology</title><addtitle>J Gastroenterol</addtitle><description>The preventive effects of contrast media containing ulinastatin (UST) and/or prednisolone (PDN) on potential complications associated with endoscopic retrograde cholangiopancreatography (ERCP) were studied in 111 patients. The incidence of abdominal pain and the elevation in the serum amylase level after ERCP were lower in the UST group than in the control group and abdominal pain and the elevated serum amylase level were almost completely suppressed in the PDN and UST/PDN groups. Based on these findings, a comparative study was conducted to evaluate the effectiveness of a combination of UST and PDN, given via the pancreatic duct, in alleviating pain symptoms in 57 patients with chronic pancreatitis and abdominal pain. The post-ERCP serum amylase level in some patients in the PDN and UST/PDN groups was lower than the pretreatment value. After ERCP, the abdominal pain that had been experienced before ERCP was relieved, and the value of the bentiromide-paraaminobenzoic acid (BT-PABA) test had improved. These results suggest that the use of contrast media containing PDN or UST/PDN in patients with chronic pancreatitis is extremely effective not only for preventing potential complications related to ERCP but also as a new diagnostic treatment method.</description><subject>Abdomen</subject><subject>Abdominal Pain - epidemiology</subject><subject>Abdominal Pain - prevention & control</subject><subject>Aged</subject><subject>Amylases - blood</subject><subject>Cholangiopancreatography, Endoscopic Retrograde - adverse effects</subject><subject>Chronic Disease</subject><subject>Contrast agents</subject><subject>Contrast Media</subject><subject>Endoscopy</subject><subject>Female</subject><subject>Glucocorticoids</subject><subject>Glycoproteins</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pain</subject><subject>Pancreatitis</subject><subject>Pancreatitis - diagnostic imaging</subject><subject>Pancreatitis - prevention & control</subject><subject>Prednisolone</subject><subject>Trypsin Inhibitors</subject><issn>0944-1174</issn><issn>1435-5922</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpdkc1LxDAQxYMoun5cvAsBwYNYnTSpSY8qrgqiFz2XNJlopJvUpEX87-3q6sHTMPN-PIb3CNlncMoA5FnroKz5OZdsjcyY4FVR1WW5TmZQC1EwJsUW2c75DYBxqNQm2axBVUyyGYkP-EEx2JhN7L2hQ0I9LDAM1MVEzWuKYbr2Opil4AefT-iYfXihJoYh6TzQBVqvv1ftw1IZOx8mYcID1cHSPqENPscuBtwlG053GfdWc4c8z6-frm6L-8ebu6uL-8IIqIairK0Bw9tSCMWEdgwcQ2aEtFw4iWilatHWRqO2LbRGV1a1zlVSaJAtlnyHHP349im-j5iHZuGzwa7TAeOYG6lUfa5YPYGH_8C3OKYw_daUUkkQlQQ-Ucc_lEkx54Su6ZNf6PTZMGiWHTSX898OJvhgZTm2Uzh_6Cp0_gXv1oRW</recordid><startdate>19970401</startdate><enddate>19970401</enddate><creator>Ohwada, M</creator><creator>Watanabe, N</creator><creator>Maeda, M</creator><creator>Gotoh, M</creator><creator>Teramoto, J</creator><creator>Moriya, H</creator><creator>Nakajima, T</creator><creator>Okamoto, T</creator><creator>Tsuji, N</creator><creator>Kobayashi, D</creator><creator>Niitsu, Y</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>8BM</scope></search><sort><creationdate>19970401</creationdate><title>New endoscopic treatment for chronic pancreatitis, using contrast media containing ulinastatin and prednisolone</title><author>Ohwada, M ; Watanabe, N ; Maeda, M ; Gotoh, M ; Teramoto, J ; Moriya, H ; Nakajima, T ; Okamoto, T ; Tsuji, N ; Kobayashi, D ; Niitsu, Y</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c405t-29dc0c3b244814af10f1e1c47d34f7eed78bed9caeadb0bca5d8bff574a07be23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Abdomen</topic><topic>Abdominal Pain - epidemiology</topic><topic>Abdominal Pain - prevention & control</topic><topic>Aged</topic><topic>Amylases - blood</topic><topic>Cholangiopancreatography, Endoscopic Retrograde - adverse effects</topic><topic>Chronic Disease</topic><topic>Contrast agents</topic><topic>Contrast Media</topic><topic>Endoscopy</topic><topic>Female</topic><topic>Glucocorticoids</topic><topic>Glycoproteins</topic><topic>Humans</topic><topic>Incidence</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pain</topic><topic>Pancreatitis</topic><topic>Pancreatitis - diagnostic imaging</topic><topic>Pancreatitis - prevention & control</topic><topic>Prednisolone</topic><topic>Trypsin Inhibitors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ohwada, M</creatorcontrib><creatorcontrib>Watanabe, N</creatorcontrib><creatorcontrib>Maeda, M</creatorcontrib><creatorcontrib>Gotoh, M</creatorcontrib><creatorcontrib>Teramoto, J</creatorcontrib><creatorcontrib>Moriya, H</creatorcontrib><creatorcontrib>Nakajima, T</creatorcontrib><creatorcontrib>Okamoto, T</creatorcontrib><creatorcontrib>Tsuji, N</creatorcontrib><creatorcontrib>Kobayashi, D</creatorcontrib><creatorcontrib>Niitsu, Y</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>ComDisDome</collection><jtitle>Journal of gastroenterology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ohwada, M</au><au>Watanabe, N</au><au>Maeda, M</au><au>Gotoh, M</au><au>Teramoto, J</au><au>Moriya, H</au><au>Nakajima, T</au><au>Okamoto, T</au><au>Tsuji, N</au><au>Kobayashi, D</au><au>Niitsu, Y</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>New endoscopic treatment for chronic pancreatitis, using contrast media containing ulinastatin and prednisolone</atitle><jtitle>Journal of gastroenterology</jtitle><addtitle>J Gastroenterol</addtitle><date>1997-04-01</date><risdate>1997</risdate><volume>32</volume><issue>2</issue><spage>216</spage><epage>221</epage><pages>216-221</pages><issn>0944-1174</issn><eissn>1435-5922</eissn><abstract>The preventive effects of contrast media containing ulinastatin (UST) and/or prednisolone (PDN) on potential complications associated with endoscopic retrograde cholangiopancreatography (ERCP) were studied in 111 patients. The incidence of abdominal pain and the elevation in the serum amylase level after ERCP were lower in the UST group than in the control group and abdominal pain and the elevated serum amylase level were almost completely suppressed in the PDN and UST/PDN groups. Based on these findings, a comparative study was conducted to evaluate the effectiveness of a combination of UST and PDN, given via the pancreatic duct, in alleviating pain symptoms in 57 patients with chronic pancreatitis and abdominal pain. The post-ERCP serum amylase level in some patients in the PDN and UST/PDN groups was lower than the pretreatment value. After ERCP, the abdominal pain that had been experienced before ERCP was relieved, and the value of the bentiromide-paraaminobenzoic acid (BT-PABA) test had improved. These results suggest that the use of contrast media containing PDN or UST/PDN in patients with chronic pancreatitis is extremely effective not only for preventing potential complications related to ERCP but also as a new diagnostic treatment method.</abstract><cop>Japan</cop><pub>Springer Nature B.V</pub><pmid>9085171</pmid><doi>10.1007/bf02936371</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0944-1174 |
| ispartof | Journal of gastroenterology, 1997-04, Vol.32 (2), p.216-221 |
| issn | 0944-1174 1435-5922 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78896819 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Abdomen Abdominal Pain - epidemiology Abdominal Pain - prevention & control Aged Amylases - blood Cholangiopancreatography, Endoscopic Retrograde - adverse effects Chronic Disease Contrast agents Contrast Media Endoscopy Female Glucocorticoids Glycoproteins Humans Incidence Male Middle Aged Pain Pancreatitis Pancreatitis - diagnostic imaging Pancreatitis - prevention & control Prednisolone Trypsin Inhibitors |
| title | New endoscopic treatment for chronic pancreatitis, using contrast media containing ulinastatin and prednisolone |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T18%3A59%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=New%20endoscopic%20treatment%20for%20chronic%20pancreatitis,%20using%20contrast%20media%20containing%20ulinastatin%20and%20prednisolone&rft.jtitle=Journal%20of%20gastroenterology&rft.au=Ohwada,%20M&rft.date=1997-04-01&rft.volume=32&rft.issue=2&rft.spage=216&rft.epage=221&rft.pages=216-221&rft.issn=0944-1174&rft.eissn=1435-5922&rft_id=info:doi/10.1007/bf02936371&rft_dat=%3Cproquest_cross%3E2787045703%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2787045703&rft_id=info:pmid/9085171&rfr_iscdi=true |