Retinoic Acid Acylation (Retinoylation) of a Nuclear Protein in the Human Acute Myeloid Leukemia Cell Line HL60

all-trans-Retinoic acid is a potent inducer in vitro of the differentiation of the human acute myeloid leukemia cell line HL60 and of fresh cells from patients with acute promyelocytic leukemia. The recent discovery of nuclear retinoic acid receptors provides a basis for understanding how retinoic a...

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Veröffentlicht in:	The Journal of biological chemistry 1989-03, Vol.264 (9), p.5159-5163
Hauptverfasser:	Takahashi, N, Breitman, T R
Format:	Artikel
Sprache:	eng
Schlagworte:	Acylation Biological and medical sciences Cell Differentiation - drug effects Cell Line Cell receptors Cell structures and functions Electrophoresis, Polyacrylamide Gel Fundamental and applied biological sciences. Psychology Humans Hydrolysis Leukemia, Myeloid, Acute - metabolism man Molecular and cellular biology Nuclear Proteins - isolation & purification Nuclear Proteins - metabolism proteins Subcellular Fractions Tretinoin - metabolism Tretinoin - pharmacology
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