Endoscopic local injection of a new drug delivery formulation, anticancer drug bound to carbon particles, for digestive cancers: pilot study

A new dosage formulation consisting of an anticancer drug bound to activated carbon particles was developed for the treatment of digestive cancer in patients in whom operation is contraindicated. The new formulation is designed to distribute higher levels of anticancer drug to the regional lymph nod...

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Veröffentlicht in:	Journal of gastroenterology 1997-03, Vol.32 (2), p.141-147
Hauptverfasser:	Hagiwara, A, Takahashi, T, Kitamura, K, Sakakura, C, Shirasu, M, Ohgaki, M, Imanishi, T, Yamasaki, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Activated carbon Adenocarcinoma - drug therapy Adenocarcinoma - mortality Adsorption Aged Aged, 80 and over Antineoplastic Agents - administration & dosage Antineoplastic Agents - pharmacokinetics Antitumor agents Cancer Carbon Carcinoma, Squamous Cell - drug therapy Carcinoma, Squamous Cell - mortality Contraindications Dosage Drug delivery Drug dosages Endoscopy Esophageal cancer Esophageal Neoplasms - drug therapy Esophageal Neoplasms - mortality Female Gastric cancer Humans Injection Injections, Intralesional Lymph nodes Lymphatic Metastasis Male Methotrexate Methotrexate - administration & dosage Methotrexate - pharmacokinetics Middle Aged Neoplasm Recurrence, Local - drug therapy Peplomycin - administration & dosage Peplomycin - pharmacokinetics Pilot Projects Stomach Neoplasms - drug therapy Stomach Neoplasms - mortality Survival Rate
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