Effects of chronic treatment with selective and nonselective antagonists on the subtypes of dopamine receptors

The effects of chronic blockade of D‐1, D‐2, or both subtypes of dopamine receptors on the densities and properties of the D‐1 and D‐2 subtypes of dopamine receptors were measured in rat brain. Animals were treated with 14 daily injections (i.p.) of the D‐1‐selective antagonist SCH‐23390, the D‐2‐se...

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Veröffentlicht in:	Synapse (New York, N.Y.) N.Y.), 1989, Vol.3 (1), p.74-82
Hauptverfasser:	McGonigle, Paul, Boyson, Sally J., Reuter, Susan, Molinoff, Perry B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Benzazepines - metabolism Benzazepines - pharmacology Chronic antagonists Corpus Striatum - drug effects Corpus Striatum - metabolism Dopamine receptors Fluphenazine - pharmacology Male Quantitative autoradiography Rats Rats, Inbred Strains Receptor regulation Receptor subtypes Receptors, Dopamine - drug effects Receptors, Dopamine - metabolism Receptors, Dopamine D1 Receptors, Dopamine D2 Spiperone - metabolism Sulpiride - pharmacology
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