A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

Macrophage type-I and type-II class-A scavenger receptors (MSR-A) are implicated in the pathological deposition of cholesterol during atherogenesis as a result of receptor-mediated uptake of modified low-density lipoproteins (mLDL) 1–6 . MSR-A can bind an extraordinarily wide range of ligands, inclu...

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Veröffentlicht in:	Nature (London) 1997-03, Vol.386 (6622), p.292-296
Hauptverfasser:	Suzuki, Hiroshi, Kurihara, Yukiko, Takeya, Motohiro, Kamada, Nobuo, Kataoka, Motoyukl, Jishage, Kouichi, Ueda, Otoya, Sakaguchi, Hisashl, Higashi, Takayuki, Suzuki, Tsukasa, Takashima, Yoshiaki, Kawabe, Yoshiki, Cynshi, Osamu, Wada, Youichiro, Honda, Makoto, Kurihara, Hiroki, Aburatani, Hiroyuki, Doi, Takefumi, Matsumoto, Akiyo, Azuma, Sadahiro, Noda, Tetsuo, Toyoda, Yutaka, Itakura, Hiroshige, Yazaki, Yoshio, Horiuchi, Seikoh, Takahashi, Kiyoshi, Kruijt, J. Kar, van Berkel, Theo J. C, Steinbrecher, Urs P, Ishibashi, Shun, Maeda, Nobuyo, Gordon, Siamon, Kodama, Tatsuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apolipoproteins E - deficiency Apolipoproteins E - metabolism Arteriosclerosis - blood Arteriosclerosis - immunology Arteriosclerosis - pathology Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cell Adhesion Cholesterol Disease Susceptibility Gene Targeting Genes Herpes Simplex - blood Herpes Simplex - immunology Humanities and Social Sciences Infections Lesions letter Lipoproteins, LDL - blood Listeriosis - blood Listeriosis - immunology Liver - microbiology Liver - pathology Macrophages, Peritoneal - metabolism Medical sciences Mice Mice, Inbred C57BL Mice, Knockout multidisciplinary Pathogens Proteins Receptors, Immunologic - deficiency Receptors, Immunologic - genetics Receptors, Immunologic - metabolism Receptors, Scavenger Rodents Scavenger Receptors, Class A Science Science (multidisciplinary) Spleen - microbiology Spleen - pathology
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