Ultrastructure of platelet formation by human megakaryocytes cultured with the Mpl ligand

The site and mechanism of platelet production by bone marrow megakaryocytes (MKs) has been the subject of extensive studies, but is still a matter of controversy. However, the recent discovery of the Mpl ligand (Mpl-l), also called megakaryocyte growth and development factor (MGDF) or thrombopoietin...

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Veröffentlicht in:	Blood 1997-04, Vol.89 (7), p.2336-2346
Hauptverfasser:	CRAMER, E. M, NOROL, F, GUICHARD, J, BRETON-GORIUS, J, VAINCHENKER, W, MASSE, J.-M, DEBILI, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biotechnology Blood Platelets - ultrastructure Bone Marrow Cells Cell Differentiation - drug effects Cell Size Cells, Cultured Cytoplasm - ultrastructure Flow Cytometry Fundamental and applied biological sciences. Psychology Humans Megakaryocytes - cytology Megakaryocytes - drug effects Megakaryocytes - ultrastructure Microscopy, Immunoelectron Microtubules - ultrastructure Recombinant Proteins - pharmacology Thrombopoietin - pharmacology
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