Protective Effects of Murine Monoclonal Antibodies in Experimental Septicemia: E. coli Antibodies Protect Against Different Serotypes of E. coli

Murine monoclonal antibodies that bind outer membrane antigens of the J5 mutant of Escherichia coli O111 :B4 were derived from spleencells of BALB/c mice immunized with killed whole cells and boosted with lipopolysaccharide (LPS) and LPS-associated proteins. Seven hybridomas were selected for their...

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Veröffentlicht in:	The Journal of infectious diseases 1989-04, Vol.159 (4), p.641-647
Hauptverfasser:	Salles, Marie-France, Mandine, Eliane, Zalisz, René, Guenounou, Moncef, Smets, Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Antibodies, Bacterial - immunology Antibodies, Monoclonal - immunology Antibodies, Monoclonal - therapeutic use Antibody Specificity Antigens Bacteria Cross Reactions Endotoxins Enzyme-Linked Immunosorbent Assay Escherichia coli Escherichia coli - immunology Escherichia coli Infections - immunology Escherichia coli Infections - prevention & control Female Hybridomas Infections Lipids Lipopolysaccharides Lipopolysaccharides - immunology Mice Monoclonal antibodies Original Articles Sepsis - immunology Sepsis - prevention & control
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