Induction of IL-15 messenger RNA and protein in human blood-derived dendritic cells: a role for IL-15 in attraction of T cells

IL-15 is a pleiotropic cytokine with IL-2-like functions. As IL-15 was shown to be mitogenic for T cells, we wondered whether human blood-derived dendritic cells (DC), as the primary stimulators of T cell responses, are able to produce IL-15. To test our hypothesis, DC were grown under serum-free co...

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Veröffentlicht in:	The Journal of immunology (1950) 1997-03, Vol.158 (6), p.2610-2615
Hauptverfasser:	Jonuleit, H, Wiedemann, K, Muller, G, Degwert, J, Hoppe, U, Knop, J, Enk, AH
Format:	Artikel
Sprache:	eng
Schlagworte:	Cells, Cultured Chemotaxis, Leukocyte - drug effects Chemotaxis, Leukocyte - immunology Dendritic Cells - metabolism Humans Immunomagnetic Separation Interleukin-15 - biosynthesis Interleukin-15 - blood Interleukin-15 - genetics Interleukin-15 - physiology Phagocytosis RNA, Messenger - biosynthesis RNA, Messenger - blood T-Lymphocytes - immunology
Online-Zugang:	Volltext
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