Role for γ-aminobutyric acid in selective vulnerability in gerbils

We tested the efficacy of various putative neuroprotective agents in the gerbil model of delayed neuronal death. The selective loss of anterior CA1 neurons of the hippocampus 4 days after 5 minutes of bilateral ischemia was complete in greater than 90% of the gerbils examined. We tested 11 agents fo...

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Veröffentlicht in:	Stroke (1970) 1989-02, Vol.20 (2), p.281-287
Hauptverfasser:	STERNAU, L. L, LUST, W. D, RICCI, A. J, RATCHESON, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Brain Ischemia - drug therapy Brain Ischemia - metabolism Cell Survival - drug effects Disease Models, Animal Female gamma-Aminobutyric Acid - physiology Gerbillinae Glycogen - metabolism Hippocampus - metabolism Hippocampus - pathology Medical sciences Nervous system involvement in other diseases. Miscellaneous Neurology Neurons - pathology Time Factors Tissue Distribution
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