Biosynthesis of Hippurate, Urea and Pyrimidines in the Fatty Liver: Studies with Rats Fed Orotic Acid or a Diet Deficient in Choline and Inositol, and with Genetically Obese (Zucker) Rats

The activities of pathways for the biosynthesis of hippurate, urea and pyrimidines in hepatocytes isolated from lean livers were compared with those from three sources of fatty liver: a) the genetically obese Zucker rat, b) Sprague-Dawley rats fed a diet deficient in choline and inositol, and c) Spr...

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Veröffentlicht in:	The Journal of nutrition 1989-02, Vol.119 (2), p.273-279
Hauptverfasser:	Maswoswe, Sibusisiwe M., Tremblay, George C.
Format:	Artikel
Sprache:	eng
Schlagworte:	ammonia Ammonium Chloride - pharmacology Animals benzoate Benzoates - pharmacology Biological and medical sciences Choline Deficiency - metabolism Diet Fatty Liver - etiology Fatty Liver - metabolism Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Gluconeogenesis - drug effects Hippurates - biosynthesis Inositol - deficiency Liver - metabolism Obesity - metabolism Ornithine - pharmacology orotate Orotic Acid - biosynthesis Pyrimidines - biosynthesis Rats Rats, Inbred Strains Rats, Zucker Urea - biosynthesis Vertebrates: anatomy and physiology, studies on body, several organs or systems Zucker rat
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