Purification and partial characterization of a novel human platelet aggregation factor in the extracellular products of Streptococcus mitis, strain Nm-65

Abstract A human blood platelet aggregation factor was purified from the extracellular products (ECP) of Streptococcus mitis, strain Nm-65 by sequential chromatography on DEAE-Sepharose CL-6B, hydroxyapatite and Superdex 75 columns. The purified factor (S. mitis-derived human platelet aggregation fa...

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Veröffentlicht in:	FEMS immunology and medical microbiology 1997-02, Vol.17 (2), p.121-129
Hauptverfasser:	Ohkuni, Hisashi, Todome, Yuko, Okibayashi, Fuminori, Watanabe, Yukino, Ohtani, Nobutaka, Ishikawa, Toshio, Asano, Goro, Kotani, Shozo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Agglomeration Amino acids Bacterial Proteins - chemistry Bacterial Proteins - isolation & purification Bacterial Proteins - pharmacology Bacteriology Biological and medical sciences Collagen Electrophoresis Extracellular Space - chemistry Extracellular Space - microbiology Female Fundamental and applied biological sciences. Psychology Gel electrophoresis Humans Hydroxyapatite Male Microbiology Middle Aged Molecular weight Organic chemistry Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Platelet Activating Factor - chemistry Platelet Activating Factor - isolation & purification Platelet Activating Factor - pharmacology Platelet aggregation Platelet Aggregation - drug effects Platelet aggregation factor Platelet Aggregation Inhibitors - pharmacology Platelet aggregation inhibitory factor Polyacrylamide Prostaglandin E1 Prostaglandin E2 Purification Sodium lauryl sulfate Streptococcus - chemistry Streptococcus - immunology Streptococcus infections Streptococcus mitis Sugar
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