Late Cardiac Deaths After Isolated Valve Replacement for Aortic Stenosis. Relation to Impaired Left Ventricular Diastolic Performance
Sixty-three patients took part in a follow-up study ten to seventeen years after valve replacement for aortic stenosis. Data obtained were used to predict cardiac deaths (n = 14) occurring in the following three-year period. The degree of residual left ventricular (LV) hypertrophy correl ated invers...
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Veröffentlicht in: | Angiology 1989-03, Vol.40 (3), p.199-208 |
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description | Sixty-three patients took part in a follow-up study ten to seventeen years after valve replacement for aortic stenosis. Data obtained were used to predict cardiac deaths (n = 14) occurring in the following three-year period. The degree of residual left ventricular (LV) hypertrophy correl ated inversely with indices for LV sys tolic and diastolic performance (radionuclide cardiography). A logis tic regression (LR) model had a posi tive predictive value for cardiac deaths of 100% (10/10) with 8% (4/53) false negatives. Evaluating LV performance indices exclusively, LR analysis showed that only peak filling rate had independent predictive value. Subnormal and normal LV ejection fractions were associated with equal three-year cardiac death rates (29%).
Depressed LV function was re lated to residual hypertrophy. Im paired diastolic performance was the prime predictor of cardiac deaths. |
doi_str_mv | 10.1177/000331978904000308 |
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Depressed LV function was re lated to residual hypertrophy. Im paired diastolic performance was the prime predictor of cardiac deaths.</description><subject>Adult</subject><subject>Aged</subject><subject>Aortic Valve - surgery</subject><subject>Aortic Valve Stenosis - mortality</subject><subject>Aortic Valve Stenosis - physiopathology</subject><subject>Aortic Valve Stenosis - surgery</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Electrocardiography</subject><subject>Endocardial and cardiac valvular diseases</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Heart</subject><subject>Heart - physiopathology</subject><subject>Heart Diseases - mortality</subject><subject>Heart Valve Prosthesis</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Prospective Studies</subject><issn>0003-3197</issn><issn>1940-1574</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1q3DAUhUVJSKeTvkChoEXozokkeyx5OUz6MzCQkL-tuZavWgXZmkpyIQ-Q967MDNkUuhDS1fnOETqEfOLsknMprxhjZckbqRpWzWem3pEFbypW8JWsTshivixm4j35EONzHlec1WfkTDS8lpIvyOsOEtINhN6CptcI6Veka5Mw0G30Los9fQL3B-kd7h1oHHBM1PhA1z4kq-l9wtFHGy8zkHHrR5o83Q57sCF7d2gSfcqeYPXkINBrCzF5l523GHLOAKPGc3JqwEX8eNyX5PHb14fNj2J38327We8KXdYyFaKBrmSSc9HVKyGhF7zSpipLZRqmDTN5BMWaTK9UD6YzKFCoTgpVcaFNuSRfDrn74H9PGFM72KjRORjRT7GVStVlldeSiAOog48xoGn3wQ4QXlrO2rn79t_us-nzMX3qBuzfLMeys35x1CFqcCbkr9v4hkkxJ1YZuzpgEX5i--ynMOZO_vfwX-eOmZ8</recordid><startdate>19890301</startdate><enddate>19890301</enddate><creator>Lund, Ole</creator><creator>Jensen, Finn Taagehøj</creator><general>SAGE Publications</general><general>Westminster</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19890301</creationdate><title>Late Cardiac Deaths After Isolated Valve Replacement for Aortic Stenosis. Relation to Impaired Left Ventricular Diastolic Performance</title><author>Lund, Ole ; Jensen, Finn Taagehøj</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c367t-29ab307112b6527ad214cf4338f90cf0f14ca809c3658dafbfe2e28b728412cf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aortic Valve - surgery</topic><topic>Aortic Valve Stenosis - mortality</topic><topic>Aortic Valve Stenosis - physiopathology</topic><topic>Aortic Valve Stenosis - surgery</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Electrocardiography</topic><topic>Endocardial and cardiac valvular diseases</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Heart</topic><topic>Heart - physiopathology</topic><topic>Heart Diseases - mortality</topic><topic>Heart Valve Prosthesis</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Prospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lund, Ole</creatorcontrib><creatorcontrib>Jensen, Finn Taagehøj</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Angiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lund, Ole</au><au>Jensen, Finn Taagehøj</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Late Cardiac Deaths After Isolated Valve Replacement for Aortic Stenosis. Relation to Impaired Left Ventricular Diastolic Performance</atitle><jtitle>Angiology</jtitle><addtitle>Angiology</addtitle><date>1989-03-01</date><risdate>1989</risdate><volume>40</volume><issue>3</issue><spage>199</spage><epage>208</epage><pages>199-208</pages><issn>0003-3197</issn><eissn>1940-1574</eissn><coden>ANGIAB</coden><abstract>Sixty-three patients took part in a follow-up study ten to seventeen years after valve replacement for aortic stenosis. Data obtained were used to predict cardiac deaths (n = 14) occurring in the following three-year period. The degree of residual left ventricular (LV) hypertrophy correl ated inversely with indices for LV sys tolic and diastolic performance (radionuclide cardiography). A logis tic regression (LR) model had a posi tive predictive value for cardiac deaths of 100% (10/10) with 8% (4/53) false negatives. Evaluating LV performance indices exclusively, LR analysis showed that only peak filling rate had independent predictive value. Subnormal and normal LV ejection fractions were associated with equal three-year cardiac death rates (29%).
Depressed LV function was re lated to residual hypertrophy. Im paired diastolic performance was the prime predictor of cardiac deaths.</abstract><cop>Thousand Oaks, CA</cop><pub>SAGE Publications</pub><pmid>2916771</pmid><doi>10.1177/000331978904000308</doi><tpages>10</tpages></addata></record> |
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subjects | Adult Aged Aortic Valve - surgery Aortic Valve Stenosis - mortality Aortic Valve Stenosis - physiopathology Aortic Valve Stenosis - surgery Biological and medical sciences Cardiology. Vascular system Electrocardiography Endocardial and cardiac valvular diseases Female Follow-Up Studies Heart Heart - physiopathology Heart Diseases - mortality Heart Valve Prosthesis Humans Male Medical sciences Middle Aged Prospective Studies |
title | Late Cardiac Deaths After Isolated Valve Replacement for Aortic Stenosis. Relation to Impaired Left Ventricular Diastolic Performance |
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