Splenic irradiation as primary therapy for prolymphocytic leukemia
A patient with prolymphocytic leukemia (PLL), a lymphoproliferative disorder that carries a poor prognosis, is presented. The disease was diagnosed at an early stage and treatment could be delayed for four years. When massive, painful splenomegaly developed, splenic irradiation (SI) was chosen as th...
Gespeichert in:
| Veröffentlicht in: | Am. J. Hematol.; (United States) 1989-03, Vol.30 (3), p.188-189 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 189 |
|---|---|
| container_issue | 3 |
| container_start_page | 188 |
| container_title | Am. J. Hematol.; (United States) |
| container_volume | 30 |
| creator | Kiss, A. Haubenstock, A. Bognar, H. Scheiderbauer, R. Ai‐Mobarak, M. Base, W. |
| description | A patient with prolymphocytic leukemia (PLL), a lymphoproliferative disorder that carries a poor prognosis, is presented. The disease was diagnosed at an early stage and treatment could be delayed for four years. When massive, painful splenomegaly developed, splenic irradiation (SI) was chosen as the primary form of therapy and an excellent systemic response could be achieved. Our observation is in agreement with preliminary studies, which advocate SI as the primary form of therapy in PLL. Furthermore, it is emphasized that an early diagnosis of PLL is necessary to establish its true course and that the prognosis may be better than originally thought. |
| doi_str_mv | 10.1002/ajh.2830300313 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_osti_</sourceid><recordid>TN_cdi_proquest_miscellaneous_78858633</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>78858633</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3963-b0cc9abe06aa74b376c63f73840b2509a0e02bbebb06d43d002cf178514f1da3</originalsourceid><addsrcrecordid>eNqFkLtPwzAQxi0EKqWwsiFFCLG1nO3EcUZAPIXEQHfr7DiqIY9ip0L573HVCNiY7nTf714fIacUFhSAXeH7asEkBw7AKd8jUwqFmEuRsX0yBS5ozKE4JEchvANQmkqYkAkrqMgEm5Kbt3VtW2cS5z2WDnvXtQmGZO1dg35I-pX1uB6SqvOx1tVDs151ZuhjR203H7ZxeEwOKqyDPRnjjCzv75a3j_OX14en2-uXueGF4HMNxhSoLQjEPNU8F0bwKucyBc0yKBAsMK2t1iDKlJfxOVPRXGY0rWiJfEbOd2O70DsVjOutWZmuba3pleCpzBiP0OUOird-bmzoVeOCsXWNre02QeVSZlLwLbjYgcZ3IXhbqfFjRUFtjVXRWPVrbGw4GydvdGPLH3x0MuoXo47BYF15bI0LP1hOqcjZFit22Jer7fDPUnX9_PjnhG9tpZCp</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>78858633</pqid></control><display><type>article</type><title>Splenic irradiation as primary therapy for prolymphocytic leukemia</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Kiss, A. ; Haubenstock, A. ; Bognar, H. ; Scheiderbauer, R. ; Ai‐Mobarak, M. ; Base, W.</creator><creatorcontrib>Kiss, A. ; Haubenstock, A. ; Bognar, H. ; Scheiderbauer, R. ; Ai‐Mobarak, M. ; Base, W. ; Univ. of Vienna (Austria)</creatorcontrib><description>A patient with prolymphocytic leukemia (PLL), a lymphoproliferative disorder that carries a poor prognosis, is presented. The disease was diagnosed at an early stage and treatment could be delayed for four years. When massive, painful splenomegaly developed, splenic irradiation (SI) was chosen as the primary form of therapy and an excellent systemic response could be achieved. Our observation is in agreement with preliminary studies, which advocate SI as the primary form of therapy in PLL. Furthermore, it is emphasized that an early diagnosis of PLL is necessary to establish its true course and that the prognosis may be better than originally thought.</description><identifier>ISSN: 0361-8609</identifier><identifier>EISSN: 1096-8652</identifier><identifier>DOI: 10.1002/ajh.2830300313</identifier><identifier>PMID: 2916562</identifier><identifier>CODEN: AJHEDD</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>550603 - Medicine- External Radiation in Therapy- (1980-) ; Biological and medical sciences ; BODY ; DISEASES ; Hematologic and hematopoietic diseases ; HEMIC DISEASES ; Humans ; IMMUNE SYSTEM DISEASES ; IRRADIATION ; LEUKEMIA ; Leukemia, Prolymphocytic - blood ; Leukemia, Prolymphocytic - radiotherapy ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; lymphoproliferative disorder ; Male ; Medical sciences ; MEDICINE ; Middle Aged ; NEOPLASMS ; NUCLEAR MEDICINE ; ORGANS ; PATIENTS ; polylymphocytic leukemia ; RADIOLOGY ; RADIOLOGY AND NUCLEAR MEDICINE ; RADIOTHERAPY ; SPLEEN ; Spleen - radiation effects ; splenic irradiation ; THERAPY</subject><ispartof>Am. J. Hematol.; (United States), 1989-03, Vol.30 (3), p.188-189</ispartof><rights>Copyright © 1989 Wiley‐Liss, Inc., A Wiley Company</rights><rights>1989 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3963-b0cc9abe06aa74b376c63f73840b2509a0e02bbebb06d43d002cf178514f1da3</citedby><cites>FETCH-LOGICAL-c3963-b0cc9abe06aa74b376c63f73840b2509a0e02bbebb06d43d002cf178514f1da3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fajh.2830300313$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fajh.2830300313$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,882,1413,27906,27907,45556,45557</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7116722$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2916562$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/6348523$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Kiss, A.</creatorcontrib><creatorcontrib>Haubenstock, A.</creatorcontrib><creatorcontrib>Bognar, H.</creatorcontrib><creatorcontrib>Scheiderbauer, R.</creatorcontrib><creatorcontrib>Ai‐Mobarak, M.</creatorcontrib><creatorcontrib>Base, W.</creatorcontrib><creatorcontrib>Univ. of Vienna (Austria)</creatorcontrib><title>Splenic irradiation as primary therapy for prolymphocytic leukemia</title><title>Am. J. Hematol.; (United States)</title><addtitle>Am J Hematol</addtitle><description>A patient with prolymphocytic leukemia (PLL), a lymphoproliferative disorder that carries a poor prognosis, is presented. The disease was diagnosed at an early stage and treatment could be delayed for four years. When massive, painful splenomegaly developed, splenic irradiation (SI) was chosen as the primary form of therapy and an excellent systemic response could be achieved. Our observation is in agreement with preliminary studies, which advocate SI as the primary form of therapy in PLL. Furthermore, it is emphasized that an early diagnosis of PLL is necessary to establish its true course and that the prognosis may be better than originally thought.</description><subject>550603 - Medicine- External Radiation in Therapy- (1980-)</subject><subject>Biological and medical sciences</subject><subject>BODY</subject><subject>DISEASES</subject><subject>Hematologic and hematopoietic diseases</subject><subject>HEMIC DISEASES</subject><subject>Humans</subject><subject>IMMUNE SYSTEM DISEASES</subject><subject>IRRADIATION</subject><subject>LEUKEMIA</subject><subject>Leukemia, Prolymphocytic - blood</subject><subject>Leukemia, Prolymphocytic - radiotherapy</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>lymphoproliferative disorder</subject><subject>Male</subject><subject>Medical sciences</subject><subject>MEDICINE</subject><subject>Middle Aged</subject><subject>NEOPLASMS</subject><subject>NUCLEAR MEDICINE</subject><subject>ORGANS</subject><subject>PATIENTS</subject><subject>polylymphocytic leukemia</subject><subject>RADIOLOGY</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>RADIOTHERAPY</subject><subject>SPLEEN</subject><subject>Spleen - radiation effects</subject><subject>splenic irradiation</subject><subject>THERAPY</subject><issn>0361-8609</issn><issn>1096-8652</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkLtPwzAQxi0EKqWwsiFFCLG1nO3EcUZAPIXEQHfr7DiqIY9ip0L573HVCNiY7nTf714fIacUFhSAXeH7asEkBw7AKd8jUwqFmEuRsX0yBS5ozKE4JEchvANQmkqYkAkrqMgEm5Kbt3VtW2cS5z2WDnvXtQmGZO1dg35I-pX1uB6SqvOx1tVDs151ZuhjR203H7ZxeEwOKqyDPRnjjCzv75a3j_OX14en2-uXueGF4HMNxhSoLQjEPNU8F0bwKucyBc0yKBAsMK2t1iDKlJfxOVPRXGY0rWiJfEbOd2O70DsVjOutWZmuba3pleCpzBiP0OUOird-bmzoVeOCsXWNre02QeVSZlLwLbjYgcZ3IXhbqfFjRUFtjVXRWPVrbGw4GydvdGPLH3x0MuoXo47BYF15bI0LP1hOqcjZFit22Jer7fDPUnX9_PjnhG9tpZCp</recordid><startdate>198903</startdate><enddate>198903</enddate><creator>Kiss, A.</creator><creator>Haubenstock, A.</creator><creator>Bognar, H.</creator><creator>Scheiderbauer, R.</creator><creator>Ai‐Mobarak, M.</creator><creator>Base, W.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>198903</creationdate><title>Splenic irradiation as primary therapy for prolymphocytic leukemia</title><author>Kiss, A. ; Haubenstock, A. ; Bognar, H. ; Scheiderbauer, R. ; Ai‐Mobarak, M. ; Base, W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3963-b0cc9abe06aa74b376c63f73840b2509a0e02bbebb06d43d002cf178514f1da3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>550603 - Medicine- External Radiation in Therapy- (1980-)</topic><topic>Biological and medical sciences</topic><topic>BODY</topic><topic>DISEASES</topic><topic>Hematologic and hematopoietic diseases</topic><topic>HEMIC DISEASES</topic><topic>Humans</topic><topic>IMMUNE SYSTEM DISEASES</topic><topic>IRRADIATION</topic><topic>LEUKEMIA</topic><topic>Leukemia, Prolymphocytic - blood</topic><topic>Leukemia, Prolymphocytic - radiotherapy</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>lymphoproliferative disorder</topic><topic>Male</topic><topic>Medical sciences</topic><topic>MEDICINE</topic><topic>Middle Aged</topic><topic>NEOPLASMS</topic><topic>NUCLEAR MEDICINE</topic><topic>ORGANS</topic><topic>PATIENTS</topic><topic>polylymphocytic leukemia</topic><topic>RADIOLOGY</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>RADIOTHERAPY</topic><topic>SPLEEN</topic><topic>Spleen - radiation effects</topic><topic>splenic irradiation</topic><topic>THERAPY</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kiss, A.</creatorcontrib><creatorcontrib>Haubenstock, A.</creatorcontrib><creatorcontrib>Bognar, H.</creatorcontrib><creatorcontrib>Scheiderbauer, R.</creatorcontrib><creatorcontrib>Ai‐Mobarak, M.</creatorcontrib><creatorcontrib>Base, W.</creatorcontrib><creatorcontrib>Univ. of Vienna (Austria)</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>Am. J. Hematol.; (United States)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kiss, A.</au><au>Haubenstock, A.</au><au>Bognar, H.</au><au>Scheiderbauer, R.</au><au>Ai‐Mobarak, M.</au><au>Base, W.</au><aucorp>Univ. of Vienna (Austria)</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Splenic irradiation as primary therapy for prolymphocytic leukemia</atitle><jtitle>Am. J. Hematol.; (United States)</jtitle><addtitle>Am J Hematol</addtitle><date>1989-03</date><risdate>1989</risdate><volume>30</volume><issue>3</issue><spage>188</spage><epage>189</epage><pages>188-189</pages><issn>0361-8609</issn><eissn>1096-8652</eissn><coden>AJHEDD</coden><abstract>A patient with prolymphocytic leukemia (PLL), a lymphoproliferative disorder that carries a poor prognosis, is presented. The disease was diagnosed at an early stage and treatment could be delayed for four years. When massive, painful splenomegaly developed, splenic irradiation (SI) was chosen as the primary form of therapy and an excellent systemic response could be achieved. Our observation is in agreement with preliminary studies, which advocate SI as the primary form of therapy in PLL. Furthermore, it is emphasized that an early diagnosis of PLL is necessary to establish its true course and that the prognosis may be better than originally thought.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>2916562</pmid><doi>10.1002/ajh.2830300313</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0361-8609 |
| ispartof | Am. J. Hematol.; (United States), 1989-03, Vol.30 (3), p.188-189 |
| issn | 0361-8609 1096-8652 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78858633 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | 550603 - Medicine- External Radiation in Therapy- (1980-) Biological and medical sciences BODY DISEASES Hematologic and hematopoietic diseases HEMIC DISEASES Humans IMMUNE SYSTEM DISEASES IRRADIATION LEUKEMIA Leukemia, Prolymphocytic - blood Leukemia, Prolymphocytic - radiotherapy Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis lymphoproliferative disorder Male Medical sciences MEDICINE Middle Aged NEOPLASMS NUCLEAR MEDICINE ORGANS PATIENTS polylymphocytic leukemia RADIOLOGY RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY SPLEEN Spleen - radiation effects splenic irradiation THERAPY |
| title | Splenic irradiation as primary therapy for prolymphocytic leukemia |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T10%3A17%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_osti_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Splenic%20irradiation%20as%20primary%20therapy%20for%20prolymphocytic%20leukemia&rft.jtitle=Am.%20J.%20Hematol.;%20(United%20States)&rft.au=Kiss,%20A.&rft.aucorp=Univ.%20of%20Vienna%20(Austria)&rft.date=1989-03&rft.volume=30&rft.issue=3&rft.spage=188&rft.epage=189&rft.pages=188-189&rft.issn=0361-8609&rft.eissn=1096-8652&rft.coden=AJHEDD&rft_id=info:doi/10.1002/ajh.2830300313&rft_dat=%3Cproquest_osti_%3E78858633%3C/proquest_osti_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=78858633&rft_id=info:pmid/2916562&rfr_iscdi=true |