Prevention of hepatitis B virus carrier state in infants according to maternal serum levels of HBV DNA

235 infants of HBeAg-carrier mothers in Hong Kong were assigned to four study groups. Groups I, II, and III received hepatitis-B (HB) vaccine at birth and at 1, 2, and 6 months. Group I also received seven monthly injections of HB immunoglobulin (HBIg), and group II received one HBIg injection at bi...

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Veröffentlicht in:	The Lancet (British edition) 1989-02, Vol.1 (8635), p.406-410
Hauptverfasser:	Ip, H M, Lelie, P N, Wong, V C, Kuhns, M C, Reesink, H W
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Carrier State - blood Carrier State - immunology Carrier State - prevention & control Carrier State - transmission Child, Preschool Chronic Disease Clinical Trials as Topic DNA, Viral - blood Evaluation Studies as Topic Female Follow-Up Studies Hepatitis B - blood Hepatitis B - immunology Hepatitis B - prevention & control Hepatitis B - transmission Hepatitis B Antibodies - analysis Hepatitis B e Antigens - analysis Hepatitis B Surface Antigens - analysis Hepatitis B virus - genetics Humans Immunization, Passive Immunoglobulins Infant Infant, Newborn Pregnancy Random Allocation Risk Factors Vaccination
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