Structural Determination of a Cyclic Metabolite of NAD+ with Intracellular Ca2+-mobilizing Activity

Incubation of NAD+ with extracts from sea urchin eggs resulted in production of a metabolite which could mobilize intracellular Ca2+ stores of the eggs. In this study we present structural evidence indicating that the metabolite is a cyclized ADP-ribose having an N-glycosyl linkage between the anome...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of biological chemistry 1989-01, Vol.264 (3), p.1608-1615
Hauptverfasser:	Lee, H C, Walseth, T F, Bratt, G T, Hayes, R N, Clapper, D L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate Ribose - analogs & derivatives Adenosine Diphosphate Ribose - analysis Adenosine Diphosphate Ribose - metabolism Animals Calcium - metabolism Chromatography, High Pressure Liquid Cyclic ADP-Ribose Magnetic Resonance Spectroscopy Mass Spectrometry Models, Molecular NAD - metabolism Oocytes - drug effects Oocytes - metabolism Sea Urchins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!