The hemopexin-like domain (C domain) of human gelatinase A (matrix metalloproteinase-2) requires Ca2+ for fibronectin and heparin binding. Binding properties of recombinant gelatinase A C domain to extracellular matrix and basement membrane components

The binding properties of the COOH-terminal hemopexin-like domain (C domain) of human gelatinase A (matrix metalloproteinase-2, 72-kDa gelatinase) were investigated to determine whether the C domain has binding affinity for extracellular matrix and basement membrane components. Recombinant C domain...

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Veröffentlicht in:	The Journal of biological chemistry 1997-03, Vol.272 (11), p.7473-7481
Hauptverfasser:	Wallon, U M, Overall, C M
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Extracellular Matrix Proteins - chemistry Extracellular Matrix Proteins - metabolism Fibronectins - metabolism Gelatinases - chemistry Gelatinases - metabolism Hemopexin - chemistry Hemopexin - metabolism Heparin - metabolism Humans Protein Binding Recombinant Proteins - chemistry Recombinant Proteins - metabolism
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