Apoptosis of immature thymocytes mediated by E2/CD99

E2/CD99 is a 32-kDa transmembrane molecule that does not belong to any known family of proteins. It appears to regulate adhesion properties of T cells as previously reported, in particular, the induction of homotypic adhesion in CD4+ CD8+ thymocytes. Apoptosis induced via E2/CD99 displays characteri...

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Veröffentlicht in:	The Journal of immunology (1950) 1997-03, Vol.158 (6), p.2543-2550
Hauptverfasser:	Bernard, G, Breittmayer, JP, de Matteis, M, Trampont, P, Hofman, P, Senik, A, Bernard, A
Format:	Artikel
Sprache:	eng
Schlagworte:	12E7 Antigen Antibodies, Monoclonal - pharmacology Antigens, CD - immunology Antigens, CD - physiology Antigens, Differentiation, T-Lymphocyte Apoptosis - immunology Caspase 1 Caspase 3 Caspases CD3 Complex CD4 Antigens CD8 Antigens Cell Adhesion Molecules - immunology Cell Adhesion Molecules - physiology Cell Differentiation - immunology Child, Preschool Cysteine Endopeptidases - drug effects Cysteine Proteinase Inhibitors - pharmacology fas Receptor - physiology Humans Immunophenotyping Jurkat Cells Lectins, C-Type T-Lymphocytes - immunology T-Lymphocytes - ultrastructure
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