Simultaneous Technetium-99m MIBI Angiography and Myocardial Perfusion Imaging
Resting first-pass radionuclide angiography (FPRNA) was performed with the myocardial perfusion agent technetium-99m MIBI. In 27 patients, it was compared with technetium-99m diethylenetriamine pentaacetic acid FPRNA. A significant correlation was present in left (r = 0.93, p less than 0.001) as wel...
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| Veröffentlicht in: | The Journal of nuclear medicine (1978) 1989-01, Vol.30 (1), p.38-44 |
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| container_title | The Journal of nuclear medicine (1978) |
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| creator | Baillet, Georges Y Mena, Ismael G Kuperus, John H Robertson, John M French, William J |
| description | Resting first-pass radionuclide angiography (FPRNA) was performed with the myocardial perfusion agent technetium-99m MIBI. In 27 patients, it was compared with technetium-99m diethylenetriamine pentaacetic acid FPRNA. A significant correlation was present in left (r = 0.93, p less than 0.001) as well as right (r = 0.92, p less than 0.001) ventricular ejection fraction measured with both radiopharmaceuticals. In 13 patients, MIBI derived segmental wall motion was compared with contrast ventriculography. A high correlation was present (p less than 0.001), and qualitative agreement was found in 38/52 segments. In 19 patients with myocardial infarction a significant correlation was present between MIBI segmental wall motion and perfusion scores (p less than 0.001). In ten patients with a history of myocardial infarction, 18 myocardial segments demonstrated diseased coronary vessels and impaired wall motion at contrast angiography. These segments were all identified by the MIBI wall motion and perfusion study. We conclude that MIBI is a promising agent for simultaneous evaluation of cardiac function and myocardial perfusion at rest. |
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In 27 patients, it was compared with technetium-99m diethylenetriamine pentaacetic acid FPRNA. A significant correlation was present in left (r = 0.93, p less than 0.001) as well as right (r = 0.92, p less than 0.001) ventricular ejection fraction measured with both radiopharmaceuticals. In 13 patients, MIBI derived segmental wall motion was compared with contrast ventriculography. A high correlation was present (p less than 0.001), and qualitative agreement was found in 38/52 segments. In 19 patients with myocardial infarction a significant correlation was present between MIBI segmental wall motion and perfusion scores (p less than 0.001). In ten patients with a history of myocardial infarction, 18 myocardial segments demonstrated diseased coronary vessels and impaired wall motion at contrast angiography. These segments were all identified by the MIBI wall motion and perfusion study. 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In 27 patients, it was compared with technetium-99m diethylenetriamine pentaacetic acid FPRNA. A significant correlation was present in left (r = 0.93, p less than 0.001) as well as right (r = 0.92, p less than 0.001) ventricular ejection fraction measured with both radiopharmaceuticals. In 13 patients, MIBI derived segmental wall motion was compared with contrast ventriculography. A high correlation was present (p less than 0.001), and qualitative agreement was found in 38/52 segments. In 19 patients with myocardial infarction a significant correlation was present between MIBI segmental wall motion and perfusion scores (p less than 0.001). In ten patients with a history of myocardial infarction, 18 myocardial segments demonstrated diseased coronary vessels and impaired wall motion at contrast angiography. These segments were all identified by the MIBI wall motion and perfusion study. We conclude that MIBI is a promising agent for simultaneous evaluation of cardiac function and myocardial perfusion at rest.</description><subject>Angiography - methods</subject><subject>Cardiomyopathies - diagnostic imaging</subject><subject>Contrast Media</subject><subject>Coronary Angiography</subject><subject>Female</subject><subject>Heart - diagnostic imaging</subject><subject>Heart - physiopathology</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myocardial Infarction - diagnostic imaging</subject><subject>Myocardial Infarction - physiopathology</subject><subject>Nitriles</subject><subject>Organometallic Compounds</subject><subject>Pentetic Acid</subject><subject>Stroke Volume</subject><subject>Technetium</subject><subject>Technetium Tc 99m Pentetate</subject><subject>Technetium Tc 99m Sestamibi</subject><subject>Tomography, Emission-Computed</subject><issn>0161-5505</issn><issn>1535-5667</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotj1FLwzAUhYMoc05_gtAXfSukSW-SPs6hs7Ch4HwuaXvbZjTpTFpk_97J9nQevo_DOVdkngCHGISQ12ROE5HEABRuyV0Ie0qpUErNyIyJlGUAc7L9MnbqR-1wmEK0w6pzOJrJxllmo23-kkdL15qh9frQHSPt6mh7HCrta6P76BN9MwUzuCi3ujWuvSc3je4DPlxyQb7fXner93jzsc5Xy03cMS7G-DRRlzUDytNGSw5cNplAZKBEDbTUjWBSIUqWVpXiJWDCK62w5HXKQDLNF-T53Hvww8-EYSysCRX2_flHIZUCmoI8iY8XcSot1sXBG6v9sbj8P_GnM-9M2_0aj4Wbqh61_5f3znJaJAVX_A9xhmSJ</recordid><startdate>19890101</startdate><enddate>19890101</enddate><creator>Baillet, Georges Y</creator><creator>Mena, Ismael G</creator><creator>Kuperus, John H</creator><creator>Robertson, John M</creator><creator>French, William J</creator><general>Soc Nuclear Med</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19890101</creationdate><title>Simultaneous Technetium-99m MIBI Angiography and Myocardial Perfusion Imaging</title><author>Baillet, Georges Y ; Mena, Ismael G ; Kuperus, John H ; Robertson, John M ; French, William J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h236t-153abd25034fa73537f96ee2586d50baf6278ee724cc83b5e13ca8eb3d42572a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Angiography - methods</topic><topic>Cardiomyopathies - diagnostic imaging</topic><topic>Contrast Media</topic><topic>Coronary Angiography</topic><topic>Female</topic><topic>Heart - diagnostic imaging</topic><topic>Heart - physiopathology</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Myocardial Infarction - diagnostic imaging</topic><topic>Myocardial Infarction - physiopathology</topic><topic>Nitriles</topic><topic>Organometallic Compounds</topic><topic>Pentetic Acid</topic><topic>Stroke Volume</topic><topic>Technetium</topic><topic>Technetium Tc 99m Pentetate</topic><topic>Technetium Tc 99m Sestamibi</topic><topic>Tomography, Emission-Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Baillet, Georges Y</creatorcontrib><creatorcontrib>Mena, Ismael G</creatorcontrib><creatorcontrib>Kuperus, John H</creatorcontrib><creatorcontrib>Robertson, John M</creatorcontrib><creatorcontrib>French, William J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of nuclear medicine (1978)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Baillet, Georges Y</au><au>Mena, Ismael G</au><au>Kuperus, John H</au><au>Robertson, John M</au><au>French, William J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Simultaneous Technetium-99m MIBI Angiography and Myocardial Perfusion Imaging</atitle><jtitle>The Journal of nuclear medicine (1978)</jtitle><addtitle>J Nucl Med</addtitle><date>1989-01-01</date><risdate>1989</risdate><volume>30</volume><issue>1</issue><spage>38</spage><epage>44</epage><pages>38-44</pages><issn>0161-5505</issn><eissn>1535-5667</eissn><abstract>Resting first-pass radionuclide angiography (FPRNA) was performed with the myocardial perfusion agent technetium-99m MIBI. In 27 patients, it was compared with technetium-99m diethylenetriamine pentaacetic acid FPRNA. A significant correlation was present in left (r = 0.93, p less than 0.001) as well as right (r = 0.92, p less than 0.001) ventricular ejection fraction measured with both radiopharmaceuticals. In 13 patients, MIBI derived segmental wall motion was compared with contrast ventriculography. A high correlation was present (p less than 0.001), and qualitative agreement was found in 38/52 segments. In 19 patients with myocardial infarction a significant correlation was present between MIBI segmental wall motion and perfusion scores (p less than 0.001). In ten patients with a history of myocardial infarction, 18 myocardial segments demonstrated diseased coronary vessels and impaired wall motion at contrast angiography. These segments were all identified by the MIBI wall motion and perfusion study. We conclude that MIBI is a promising agent for simultaneous evaluation of cardiac function and myocardial perfusion at rest.</abstract><cop>United States</cop><pub>Soc Nuclear Med</pub><pmid>2642955</pmid><tpages>7</tpages></addata></record> |
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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Angiography - methods Cardiomyopathies - diagnostic imaging Contrast Media Coronary Angiography Female Heart - diagnostic imaging Heart - physiopathology Humans Male Middle Aged Myocardial Infarction - diagnostic imaging Myocardial Infarction - physiopathology Nitriles Organometallic Compounds Pentetic Acid Stroke Volume Technetium Technetium Tc 99m Pentetate Technetium Tc 99m Sestamibi Tomography, Emission-Computed |
| title | Simultaneous Technetium-99m MIBI Angiography and Myocardial Perfusion Imaging |
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