The prevalence of gastro-oesophageal reflux disease based on non-specific symptoms in institutionalized, intellectually disabled individuals
OBJECTIVE:The prevalence of gastro-oesophageal reflux disease (GORD) in randomly selected, institutionalized, intellectually disabled individuals (IQ
Gespeichert in:
| Veröffentlicht in: | European journal of gastroenterology & hepatology 1997-02, Vol.9 (2), p.187-190 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 190 |
|---|---|
| container_issue | 2 |
| container_start_page | 187 |
| container_title | European journal of gastroenterology & hepatology |
| container_volume | 9 |
| creator | Böhmer, Clarisse J.M Klinkenberg-Knol, Elly C Niezen-de Boer, Riet C Meuwissen, Stefan G.M |
| description | OBJECTIVE:The prevalence of gastro-oesophageal reflux disease (GORD) in randomly selected, institutionalized, intellectually disabled individuals (IQ |
| doi_str_mv | 10.1097/00042737-199702000-00015 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_78849020</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>78849020</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4505-d46353f9655bfe71f5647a15682b1915f8b6a2933c711bce7770a196797ee1753</originalsourceid><addsrcrecordid>eNp1UsGOFCEQJUazjqufYMLBeLIVmgaao9moa7KJlzXxRmi6egdlmpaidx2_wY9e1hnnZgJUqHr1gPcghHL2ljOj3zHGulYL3XBjNGvrtqmTy0dkwzstGql6_ZhsmJFdowz_9pQ8Q_xeEVpwfUbODJO9Eu2G_LneAl0y3LoIsweaJnrjsOTUJMC0bN0NuEgzTHH9RceA4BDoUJeRppnOaW5wAR-m4Cnud0tJO6RhrgNLKGsJaXYx_IbxTU0ViBF8WV2M-wcuN8RKE-Yx3IaxZvE5eTLVAC-O8Zx8_fjh-uKyufry6fPF-6vGd5LJZuyUkGIySsphAs0nqTrteH1zO3DD5dQPyrVGCK85HzxorZnjRmmjAbiW4py8PvAuOf1cAYvdBfT1dm6GtKLVfd-ZqmoF9gegzwmxqmCXHHYu7y1n9sEI-88IezLC_jWitr48nrEOOxhPjUfla_3Vse7QuzhlN_uAJ1irGGdMVVh3gN2lWCDjj7jeQbbb6krZ2v99A3EPU3qikA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>78849020</pqid></control><display><type>article</type><title>The prevalence of gastro-oesophageal reflux disease based on non-specific symptoms in institutionalized, intellectually disabled individuals</title><source>MEDLINE</source><source>Journals@Ovid Ovid Autoload</source><creator>Böhmer, Clarisse J.M ; Klinkenberg-Knol, Elly C ; Niezen-de Boer, Riet C ; Meuwissen, Stefan G.M</creator><creatorcontrib>Böhmer, Clarisse J.M ; Klinkenberg-Knol, Elly C ; Niezen-de Boer, Riet C ; Meuwissen, Stefan G.M</creatorcontrib><description>OBJECTIVE:The prevalence of gastro-oesophageal reflux disease (GORD) in randomly selected, institutionalized, intellectually disabled individuals (IQ<50) in The Netherlands is high.
DESIGN:In this study we investigated the prevalence of GORD and reflux oesophagitis (RO) in intellectually disabled individuals specifically selected for symptoms such asbehavioural difficulties such as automutilation, food refusal, fear and restlessness, vomiting, regurgitation and rumination. Predisposing factors were also evaluated.
METHODS:One hundred and ten individuals from one institute underwent a 24-h oesophageal pH test and were scored for predisposing factors and non-specific reflux symptoms. A pathological pH test was defined as a pH lower than 4 more than 4.5% of the measured time. Subjects with a pathological pH test (patients) were compared to those with a normal pH test (controls).
RESULTS:In seven cases (6.4%) the test failed for technical reasons. In 57 (55.3%) cases a pathological pH test was found. RO was diagnosed in 33 (64.7%) patients. The use of anticonvulsant drugs and cerebral palsy appeared to be predisposing factors, while the non-specific reflux symptoms did not discriminate for GORD.
CONCLUSION:The prevalence of GORD was equal in a randomly selected group of intellectually disabled individuals, and in this group, specifically selected on account of possible reflux symptoms. This study confirms that in this particular group, it is nearly impossible to discriminate for the diagnosis of GORD on non-specific reflux symptoms only. However, GORD may be suspected where there are certain predisposing factors, particularly cerebral palsy and use of anticonvulsant drugs.</description><identifier>ISSN: 0954-691X</identifier><identifier>EISSN: 1473-5687</identifier><identifier>DOI: 10.1097/00042737-199702000-00015</identifier><identifier>PMID: 9058632</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott-Raven Publishers</publisher><subject>Adult ; Biological and medical sciences ; Causality ; Esophagus ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Gastroesophageal Reflux - complications ; Gastroesophageal Reflux - diagnosis ; Gastroesophageal Reflux - epidemiology ; Humans ; Hydrogen-Ion Concentration ; Institutionalization - statistics & numerical data ; Intellectual Disability - complications ; Male ; Medical sciences ; Other diseases. Semiology ; Prevalence</subject><ispartof>European journal of gastroenterology & hepatology, 1997-02, Vol.9 (2), p.187-190</ispartof><rights>Lippincott-Raven Publishers.</rights><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4505-d46353f9655bfe71f5647a15682b1915f8b6a2933c711bce7770a196797ee1753</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2601006$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9058632$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Böhmer, Clarisse J.M</creatorcontrib><creatorcontrib>Klinkenberg-Knol, Elly C</creatorcontrib><creatorcontrib>Niezen-de Boer, Riet C</creatorcontrib><creatorcontrib>Meuwissen, Stefan G.M</creatorcontrib><title>The prevalence of gastro-oesophageal reflux disease based on non-specific symptoms in institutionalized, intellectually disabled individuals</title><title>European journal of gastroenterology & hepatology</title><addtitle>Eur J Gastroenterol Hepatol</addtitle><description>OBJECTIVE:The prevalence of gastro-oesophageal reflux disease (GORD) in randomly selected, institutionalized, intellectually disabled individuals (IQ<50) in The Netherlands is high.
DESIGN:In this study we investigated the prevalence of GORD and reflux oesophagitis (RO) in intellectually disabled individuals specifically selected for symptoms such asbehavioural difficulties such as automutilation, food refusal, fear and restlessness, vomiting, regurgitation and rumination. Predisposing factors were also evaluated.
METHODS:One hundred and ten individuals from one institute underwent a 24-h oesophageal pH test and were scored for predisposing factors and non-specific reflux symptoms. A pathological pH test was defined as a pH lower than 4 more than 4.5% of the measured time. Subjects with a pathological pH test (patients) were compared to those with a normal pH test (controls).
RESULTS:In seven cases (6.4%) the test failed for technical reasons. In 57 (55.3%) cases a pathological pH test was found. RO was diagnosed in 33 (64.7%) patients. The use of anticonvulsant drugs and cerebral palsy appeared to be predisposing factors, while the non-specific reflux symptoms did not discriminate for GORD.
CONCLUSION:The prevalence of GORD was equal in a randomly selected group of intellectually disabled individuals, and in this group, specifically selected on account of possible reflux symptoms. This study confirms that in this particular group, it is nearly impossible to discriminate for the diagnosis of GORD on non-specific reflux symptoms only. However, GORD may be suspected where there are certain predisposing factors, particularly cerebral palsy and use of anticonvulsant drugs.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Causality</subject><subject>Esophagus</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Gastroesophageal Reflux - complications</subject><subject>Gastroesophageal Reflux - diagnosis</subject><subject>Gastroesophageal Reflux - epidemiology</subject><subject>Humans</subject><subject>Hydrogen-Ion Concentration</subject><subject>Institutionalization - statistics & numerical data</subject><subject>Intellectual Disability - complications</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Other diseases. Semiology</subject><subject>Prevalence</subject><issn>0954-691X</issn><issn>1473-5687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1UsGOFCEQJUazjqufYMLBeLIVmgaao9moa7KJlzXxRmi6egdlmpaidx2_wY9e1hnnZgJUqHr1gPcghHL2ljOj3zHGulYL3XBjNGvrtqmTy0dkwzstGql6_ZhsmJFdowz_9pQ8Q_xeEVpwfUbODJO9Eu2G_LneAl0y3LoIsweaJnrjsOTUJMC0bN0NuEgzTHH9RceA4BDoUJeRppnOaW5wAR-m4Cnud0tJO6RhrgNLKGsJaXYx_IbxTU0ViBF8WV2M-wcuN8RKE-Yx3IaxZvE5eTLVAC-O8Zx8_fjh-uKyufry6fPF-6vGd5LJZuyUkGIySsphAs0nqTrteH1zO3DD5dQPyrVGCK85HzxorZnjRmmjAbiW4py8PvAuOf1cAYvdBfT1dm6GtKLVfd-ZqmoF9gegzwmxqmCXHHYu7y1n9sEI-88IezLC_jWitr48nrEOOxhPjUfla_3Vse7QuzhlN_uAJ1irGGdMVVh3gN2lWCDjj7jeQbbb6krZ2v99A3EPU3qikA</recordid><startdate>199702</startdate><enddate>199702</enddate><creator>Böhmer, Clarisse J.M</creator><creator>Klinkenberg-Knol, Elly C</creator><creator>Niezen-de Boer, Riet C</creator><creator>Meuwissen, Stefan G.M</creator><general>Lippincott-Raven Publishers</general><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199702</creationdate><title>The prevalence of gastro-oesophageal reflux disease based on non-specific symptoms in institutionalized, intellectually disabled individuals</title><author>Böhmer, Clarisse J.M ; Klinkenberg-Knol, Elly C ; Niezen-de Boer, Riet C ; Meuwissen, Stefan G.M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4505-d46353f9655bfe71f5647a15682b1915f8b6a2933c711bce7770a196797ee1753</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Causality</topic><topic>Esophagus</topic><topic>Female</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Gastroesophageal Reflux - complications</topic><topic>Gastroesophageal Reflux - diagnosis</topic><topic>Gastroesophageal Reflux - epidemiology</topic><topic>Humans</topic><topic>Hydrogen-Ion Concentration</topic><topic>Institutionalization - statistics & numerical data</topic><topic>Intellectual Disability - complications</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Other diseases. Semiology</topic><topic>Prevalence</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Böhmer, Clarisse J.M</creatorcontrib><creatorcontrib>Klinkenberg-Knol, Elly C</creatorcontrib><creatorcontrib>Niezen-de Boer, Riet C</creatorcontrib><creatorcontrib>Meuwissen, Stefan G.M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of gastroenterology & hepatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Böhmer, Clarisse J.M</au><au>Klinkenberg-Knol, Elly C</au><au>Niezen-de Boer, Riet C</au><au>Meuwissen, Stefan G.M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The prevalence of gastro-oesophageal reflux disease based on non-specific symptoms in institutionalized, intellectually disabled individuals</atitle><jtitle>European journal of gastroenterology & hepatology</jtitle><addtitle>Eur J Gastroenterol Hepatol</addtitle><date>1997-02</date><risdate>1997</risdate><volume>9</volume><issue>2</issue><spage>187</spage><epage>190</epage><pages>187-190</pages><issn>0954-691X</issn><eissn>1473-5687</eissn><abstract>OBJECTIVE:The prevalence of gastro-oesophageal reflux disease (GORD) in randomly selected, institutionalized, intellectually disabled individuals (IQ<50) in The Netherlands is high.
DESIGN:In this study we investigated the prevalence of GORD and reflux oesophagitis (RO) in intellectually disabled individuals specifically selected for symptoms such asbehavioural difficulties such as automutilation, food refusal, fear and restlessness, vomiting, regurgitation and rumination. Predisposing factors were also evaluated.
METHODS:One hundred and ten individuals from one institute underwent a 24-h oesophageal pH test and were scored for predisposing factors and non-specific reflux symptoms. A pathological pH test was defined as a pH lower than 4 more than 4.5% of the measured time. Subjects with a pathological pH test (patients) were compared to those with a normal pH test (controls).
RESULTS:In seven cases (6.4%) the test failed for technical reasons. In 57 (55.3%) cases a pathological pH test was found. RO was diagnosed in 33 (64.7%) patients. The use of anticonvulsant drugs and cerebral palsy appeared to be predisposing factors, while the non-specific reflux symptoms did not discriminate for GORD.
CONCLUSION:The prevalence of GORD was equal in a randomly selected group of intellectually disabled individuals, and in this group, specifically selected on account of possible reflux symptoms. This study confirms that in this particular group, it is nearly impossible to discriminate for the diagnosis of GORD on non-specific reflux symptoms only. However, GORD may be suspected where there are certain predisposing factors, particularly cerebral palsy and use of anticonvulsant drugs.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott-Raven Publishers</pub><pmid>9058632</pmid><doi>10.1097/00042737-199702000-00015</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0954-691X |
| ispartof | European journal of gastroenterology & hepatology, 1997-02, Vol.9 (2), p.187-190 |
| issn | 0954-691X 1473-5687 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78849020 |
| source | MEDLINE; Journals@Ovid Ovid Autoload |
| subjects | Adult Biological and medical sciences Causality Esophagus Female Gastroenterology. Liver. Pancreas. Abdomen Gastroesophageal Reflux - complications Gastroesophageal Reflux - diagnosis Gastroesophageal Reflux - epidemiology Humans Hydrogen-Ion Concentration Institutionalization - statistics & numerical data Intellectual Disability - complications Male Medical sciences Other diseases. Semiology Prevalence |
| title | The prevalence of gastro-oesophageal reflux disease based on non-specific symptoms in institutionalized, intellectually disabled individuals |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T13%3A10%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20prevalence%20of%20gastro-oesophageal%20reflux%20disease%20based%20on%20non-specific%20symptoms%20in%20institutionalized,%20intellectually%20disabled%20individuals&rft.jtitle=European%20journal%20of%20gastroenterology%20&%20hepatology&rft.au=B%C3%B6hmer,%20Clarisse%20J.M&rft.date=1997-02&rft.volume=9&rft.issue=2&rft.spage=187&rft.epage=190&rft.pages=187-190&rft.issn=0954-691X&rft.eissn=1473-5687&rft_id=info:doi/10.1097/00042737-199702000-00015&rft_dat=%3Cproquest_cross%3E78849020%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=78849020&rft_id=info:pmid/9058632&rfr_iscdi=true |