Treatment with anti-L3T4 (CD4) monoclonal antibody reduces the inflammatory response in toxoplasmic encephalitis

Toxoplasma gondii is an important cause of disease of the central nervous system in patients with AIDS. Among the variety of immunologic disorders encountered by AIDS patients is a depletion of CD4+ subpopulation of lymphocytes. In order to determine the role of this population of T lymphocytes in t...

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Veröffentlicht in:	The Journal of immunology (1950) 1989-02, Vol.142 (3), p.954-958
Hauptverfasser:	Israelski, DM, Araujo, FG, Conley, FK, Suzuki, Y, Sharma, S, Remington, JS
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - therapeutic use Antigens, Differentiation, T-Lymphocyte - immunology Biological and medical sciences Brain - pathology Encephalitis - immunology Encephalitis - pathology Encephalitis - therapy Female Fundamental and applied biological sciences. Psychology Fundamental immunology Hypersensitivity, Delayed - pathology Immunobiology Lymphoid cells: ontogeny, maturation, markers, receptors, circulation and recirculation Mice Mice, Inbred BALB C Mice, Inbred C3H Rats Toxoplasma gondii Toxoplasmosis, Animal - immunology Toxoplasmosis, Animal - pathology Toxoplasmosis, Animal - therapy
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