Evidence for superantigenic activity during murine malaria infection

TCR V beta usage was examined in C57BL/6 mice infected with Plasmodium yoelii. In addition to a polyclonal T cell activation, already described, a superantigenic-like activity was observed during the acute infection. This superantigenic activity induces a preferential deletion without prior expansio...

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Veröffentlicht in:	International immunology 1997-01, Vol.9 (1), p.17-25
Hauptverfasser:	Pied, S, Voegtle, D, Marussig, M, Rénia, L, Miltgen, F, Mazier, D, Cazenave, P A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Antigens, Protozoan - metabolism Clonal Deletion Erythrocytes - immunology Erythrocytes - parasitology Immunophenotyping Malaria - immunology Malaria - parasitology Mice Mice, Inbred BALB C Mice, Inbred C57BL Parasitemia - immunology Plasmodium yoelii Plasmodium yoelii - growth & development Plasmodium yoelii - immunology Receptors, Antigen, T-Cell, alpha-beta - genetics Superantigens - metabolism T-Lymphocyte Subsets - classification
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