Polyamines are sufficient to drive the transport of the precursor of ornithine carbamoyltransferase into rat liver mitochondria: Possible effect on mitochondrial membranes
The polyamines spermidine, spermine and putrescine, by themselves, at physiological concentrations, induce the transport of the precursor of ornithine carbamoyltransferase into isolated rat liver mitochondria. The presence of polyamines in the transport medium results in the approach of both mitocho...
Gespeichert in:
| Veröffentlicht in: | Biochemical and biophysical research communications 1989-01, Vol.158 (1), p.287-293 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 293 |
|---|---|
| container_issue | 1 |
| container_start_page | 287 |
| container_title | Biochemical and biophysical research communications |
| container_volume | 158 |
| creator | Marcote, M.J. González-Bosch, C. Miralles, V.J. Hernández-Yago, J. Grisolía, S. |
| description | The polyamines spermidine, spermine and putrescine, by themselves, at physiological concentrations, induce the transport of the precursor of ornithine carbamoyltransferase into isolated rat liver mitochondria. The presence of polyamines in the transport medium results in the approach of both mitochondrial membranes, suggesting a possible role of these molecules in the transport of the precursor of ornithine carbamoyltransferase into mitochondria, by the formation and/or stabilization of mitochondrial structures involved in the transport system. |
| doi_str_mv | 10.1016/S0006-291X(89)80210-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_78846599</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0006291X89802104</els_id><sourcerecordid>78846599</sourcerecordid><originalsourceid>FETCH-LOGICAL-c420t-32e7fe7c95758a5bed244101d08e88027573617ac2f763c3576b13998d08a7c73</originalsourceid><addsrcrecordid>eNqFUU2LFDEQDaKss6M_YSEHEffQmnR3OomXRRa_YMEFFbyFdLrCRLo7Y5JemN_kn7TmgwFPewghr169qrxHyBVnbznj3bvvjLGuqjX_9Ubpa8Vqzqr2CVlxplmFj_YpWZ0pz8llzr8Z47zt9AW5QKxuBVuRv_dx3NkpzJCpTUDz4n1wAeZCS6RDCg9AywZPsnPexlRo9Adgm8AtKce0B2KaQ9mgCHU29XaKu_HQ4CHZDDTMqJVsoSPKJTqFEt0mzqhu39P7mHPoR6DgPTjUn_8jjHSCqUcxyC_IM2_HDC9P95r8_PTxx-2X6u7b56-3H-4q19asVE0N0oN0WkihrOhhqNsWLRuYAoU-SSGbjkvrai-7xjVCdj1vtFZIsNLJZk1eH3W3Kf5ZIBczhexgHHGJuGQjlWo7ofWjRC64kByHrIk4El3C3ybwZpvCZNPOcGb2aZpDmmYflVHaHNI0LfZdnQYs_QTDuesUH9Zfneo2Ozt6tMmFfKZ1inUN3-95c6QBuvYQIJm8j9jBEDDFYoYYHlnkHzINv_M</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>15157176</pqid></control><display><type>article</type><title>Polyamines are sufficient to drive the transport of the precursor of ornithine carbamoyltransferase into rat liver mitochondria: Possible effect on mitochondrial membranes</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Marcote, M.J. ; González-Bosch, C. ; Miralles, V.J. ; Hernández-Yago, J. ; Grisolía, S.</creator><creatorcontrib>Marcote, M.J. ; González-Bosch, C. ; Miralles, V.J. ; Hernández-Yago, J. ; Grisolía, S.</creatorcontrib><description>The polyamines spermidine, spermine and putrescine, by themselves, at physiological concentrations, induce the transport of the precursor of ornithine carbamoyltransferase into isolated rat liver mitochondria. The presence of polyamines in the transport medium results in the approach of both mitochondrial membranes, suggesting a possible role of these molecules in the transport of the precursor of ornithine carbamoyltransferase into mitochondria, by the formation and/or stabilization of mitochondrial structures involved in the transport system.</description><identifier>ISSN: 0006-291X</identifier><identifier>EISSN: 1090-2104</identifier><identifier>DOI: 10.1016/S0006-291X(89)80210-4</identifier><identifier>PMID: 2912450</identifier><identifier>CODEN: BBRCA9</identifier><language>eng</language><publisher>San Diego, CA: Elsevier Inc</publisher><subject>Animals ; Biological and medical sciences ; Biological Transport - drug effects ; Cell physiology ; Enzyme Precursors - genetics ; Fundamental and applied biological sciences. Psychology ; Intracellular Membranes - physiology ; liver ; Membrane and intracellular transports ; Microscopy, Electron ; mitochondria ; Mitochondria, Liver - enzymology ; Mitochondria, Liver - ultrastructure ; Molecular and cellular biology ; Ornithine Carbamoyltransferase - genetics ; ornithine decarboxylase ; Protein Processing, Post-Translational - drug effects ; Putrescine - pharmacology ; Rats ; RNA, Messenger - genetics ; Spermidine - pharmacology ; Spermine - pharmacology</subject><ispartof>Biochemical and biophysical research communications, 1989-01, Vol.158 (1), p.287-293</ispartof><rights>1989 Academic Press, Inc.</rights><rights>1990 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c420t-32e7fe7c95758a5bed244101d08e88027573617ac2f763c3576b13998d08a7c73</citedby><cites>FETCH-LOGICAL-c420t-32e7fe7c95758a5bed244101d08e88027573617ac2f763c3576b13998d08a7c73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0006-291X(89)80210-4$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27923,27924,45994</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6806319$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2912450$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Marcote, M.J.</creatorcontrib><creatorcontrib>González-Bosch, C.</creatorcontrib><creatorcontrib>Miralles, V.J.</creatorcontrib><creatorcontrib>Hernández-Yago, J.</creatorcontrib><creatorcontrib>Grisolía, S.</creatorcontrib><title>Polyamines are sufficient to drive the transport of the precursor of ornithine carbamoyltransferase into rat liver mitochondria: Possible effect on mitochondrial membranes</title><title>Biochemical and biophysical research communications</title><addtitle>Biochem Biophys Res Commun</addtitle><description>The polyamines spermidine, spermine and putrescine, by themselves, at physiological concentrations, induce the transport of the precursor of ornithine carbamoyltransferase into isolated rat liver mitochondria. The presence of polyamines in the transport medium results in the approach of both mitochondrial membranes, suggesting a possible role of these molecules in the transport of the precursor of ornithine carbamoyltransferase into mitochondria, by the formation and/or stabilization of mitochondrial structures involved in the transport system.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Biological Transport - drug effects</subject><subject>Cell physiology</subject><subject>Enzyme Precursors - genetics</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Intracellular Membranes - physiology</subject><subject>liver</subject><subject>Membrane and intracellular transports</subject><subject>Microscopy, Electron</subject><subject>mitochondria</subject><subject>Mitochondria, Liver - enzymology</subject><subject>Mitochondria, Liver - ultrastructure</subject><subject>Molecular and cellular biology</subject><subject>Ornithine Carbamoyltransferase - genetics</subject><subject>ornithine decarboxylase</subject><subject>Protein Processing, Post-Translational - drug effects</subject><subject>Putrescine - pharmacology</subject><subject>Rats</subject><subject>RNA, Messenger - genetics</subject><subject>Spermidine - pharmacology</subject><subject>Spermine - pharmacology</subject><issn>0006-291X</issn><issn>1090-2104</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUU2LFDEQDaKss6M_YSEHEffQmnR3OomXRRa_YMEFFbyFdLrCRLo7Y5JemN_kn7TmgwFPewghr169qrxHyBVnbznj3bvvjLGuqjX_9Ubpa8Vqzqr2CVlxplmFj_YpWZ0pz8llzr8Z47zt9AW5QKxuBVuRv_dx3NkpzJCpTUDz4n1wAeZCS6RDCg9AywZPsnPexlRo9Adgm8AtKce0B2KaQ9mgCHU29XaKu_HQ4CHZDDTMqJVsoSPKJTqFEt0mzqhu39P7mHPoR6DgPTjUn_8jjHSCqUcxyC_IM2_HDC9P95r8_PTxx-2X6u7b56-3H-4q19asVE0N0oN0WkihrOhhqNsWLRuYAoU-SSGbjkvrai-7xjVCdj1vtFZIsNLJZk1eH3W3Kf5ZIBczhexgHHGJuGQjlWo7ofWjRC64kByHrIk4El3C3ybwZpvCZNPOcGb2aZpDmmYflVHaHNI0LfZdnQYs_QTDuesUH9Zfneo2Ozt6tMmFfKZ1inUN3-95c6QBuvYQIJm8j9jBEDDFYoYYHlnkHzINv_M</recordid><startdate>19890116</startdate><enddate>19890116</enddate><creator>Marcote, M.J.</creator><creator>González-Bosch, C.</creator><creator>Miralles, V.J.</creator><creator>Hernández-Yago, J.</creator><creator>Grisolía, S.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>M7Z</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>19890116</creationdate><title>Polyamines are sufficient to drive the transport of the precursor of ornithine carbamoyltransferase into rat liver mitochondria: Possible effect on mitochondrial membranes</title><author>Marcote, M.J. ; González-Bosch, C. ; Miralles, V.J. ; Hernández-Yago, J. ; Grisolía, S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c420t-32e7fe7c95758a5bed244101d08e88027573617ac2f763c3576b13998d08a7c73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Biological Transport - drug effects</topic><topic>Cell physiology</topic><topic>Enzyme Precursors - genetics</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Intracellular Membranes - physiology</topic><topic>liver</topic><topic>Membrane and intracellular transports</topic><topic>Microscopy, Electron</topic><topic>mitochondria</topic><topic>Mitochondria, Liver - enzymology</topic><topic>Mitochondria, Liver - ultrastructure</topic><topic>Molecular and cellular biology</topic><topic>Ornithine Carbamoyltransferase - genetics</topic><topic>ornithine decarboxylase</topic><topic>Protein Processing, Post-Translational - drug effects</topic><topic>Putrescine - pharmacology</topic><topic>Rats</topic><topic>RNA, Messenger - genetics</topic><topic>Spermidine - pharmacology</topic><topic>Spermine - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Marcote, M.J.</creatorcontrib><creatorcontrib>González-Bosch, C.</creatorcontrib><creatorcontrib>Miralles, V.J.</creatorcontrib><creatorcontrib>Hernández-Yago, J.</creatorcontrib><creatorcontrib>Grisolía, S.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Biochemical and biophysical research communications</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Marcote, M.J.</au><au>González-Bosch, C.</au><au>Miralles, V.J.</au><au>Hernández-Yago, J.</au><au>Grisolía, S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Polyamines are sufficient to drive the transport of the precursor of ornithine carbamoyltransferase into rat liver mitochondria: Possible effect on mitochondrial membranes</atitle><jtitle>Biochemical and biophysical research communications</jtitle><addtitle>Biochem Biophys Res Commun</addtitle><date>1989-01-16</date><risdate>1989</risdate><volume>158</volume><issue>1</issue><spage>287</spage><epage>293</epage><pages>287-293</pages><issn>0006-291X</issn><eissn>1090-2104</eissn><coden>BBRCA9</coden><abstract>The polyamines spermidine, spermine and putrescine, by themselves, at physiological concentrations, induce the transport of the precursor of ornithine carbamoyltransferase into isolated rat liver mitochondria. The presence of polyamines in the transport medium results in the approach of both mitochondrial membranes, suggesting a possible role of these molecules in the transport of the precursor of ornithine carbamoyltransferase into mitochondria, by the formation and/or stabilization of mitochondrial structures involved in the transport system.</abstract><cop>San Diego, CA</cop><pub>Elsevier Inc</pub><pmid>2912450</pmid><doi>10.1016/S0006-291X(89)80210-4</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-291X |
| ispartof | Biochemical and biophysical research communications, 1989-01, Vol.158 (1), p.287-293 |
| issn | 0006-291X 1090-2104 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78846599 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Animals Biological and medical sciences Biological Transport - drug effects Cell physiology Enzyme Precursors - genetics Fundamental and applied biological sciences. Psychology Intracellular Membranes - physiology liver Membrane and intracellular transports Microscopy, Electron mitochondria Mitochondria, Liver - enzymology Mitochondria, Liver - ultrastructure Molecular and cellular biology Ornithine Carbamoyltransferase - genetics ornithine decarboxylase Protein Processing, Post-Translational - drug effects Putrescine - pharmacology Rats RNA, Messenger - genetics Spermidine - pharmacology Spermine - pharmacology |
| title | Polyamines are sufficient to drive the transport of the precursor of ornithine carbamoyltransferase into rat liver mitochondria: Possible effect on mitochondrial membranes |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T14%3A25%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Polyamines%20are%20sufficient%20to%20drive%20the%20transport%20of%20the%20precursor%20of%20ornithine%20carbamoyltransferase%20into%20rat%20liver%20mitochondria:%20Possible%20effect%20on%20mitochondrial%20membranes&rft.jtitle=Biochemical%20and%20biophysical%20research%20communications&rft.au=Marcote,%20M.J.&rft.date=1989-01-16&rft.volume=158&rft.issue=1&rft.spage=287&rft.epage=293&rft.pages=287-293&rft.issn=0006-291X&rft.eissn=1090-2104&rft.coden=BBRCA9&rft_id=info:doi/10.1016/S0006-291X(89)80210-4&rft_dat=%3Cproquest_cross%3E78846599%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=15157176&rft_id=info:pmid/2912450&rft_els_id=S0006291X89802104&rfr_iscdi=true |