M2 subunit of ribonucleotide reductase is a target of cyclic AMP-dependent protein kinase

Cyclic AMP arrests T lymphocytes in the G1 phase of the cell cycle, and prolonged exposure results in cytolysis. Both of these effects require cyclic AMP‐dependent protein kinase. We recently observed that some S49 mouse T lymphoma cell lines selected for hydroxyurea resistance were not arrested in...

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Veröffentlicht in:	Journal of cellular physiology 1989-01, Vol.138 (1), p.129-136
Hauptverfasser:	Albert, Daniel A., Nodzenski, Edwardine
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Cell Line Cyclic AMP - pharmacology Electrophoresis, Polyacrylamide Gel Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology Hydroxyurea - pharmacology lymphocytes T Lymphoma - enzymology Macromolecular Substances mice Oxidoreductases Phosphorylation Protein Kinases - metabolism ribonucleotide reductase Ribonucleotide Reductases - analysis
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