Effect of morphine on striatal dopamine metabolism and ascorbic and uric acid release in freely moving rats

Recent ex vivo findings have shown that morphine increases dopamine (DA) and xanthine oxidative metabolism and ascorbic acid (AA) oxidation in the rat striatum. In the present study, we evaluated the effects of subcutaneous daily morphine (20 mg/kg) administration on DA, dihydroxyphenylacetic acid (...

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Veröffentlicht in:	Brain research 1997-01, Vol.745 (1-2), p.173-182
Hauptverfasser:	Enrico, P, Esposito, G, Mura, M A, Fresu, L, De Natale, G, Miele, E, Desole, M S, Miele, M
Format:	Artikel
Sprache:	eng
Schlagworte:	3,4-Dihydroxyphenylacetic Acid - metabolism Animals Ascorbic Acid - metabolism Dopamine - metabolism Homovanillic Acid - metabolism Male Microdialysis Morphine - pharmacology Narcotics - pharmacology Neostriatum - drug effects Neostriatum - metabolism Rats Rats, Wistar Uric Acid - metabolism
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