H19 in normal development and neoplasia

Since our previous review (De Groot and Hochberg, 1993), a large number of studies regarding the role of genomic imprinting in normal development, and in non-neoplastic and neoplastic diseases has been reported. Although a number of very interesting but more general reviews have been published (Fein...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Molecular reproduction and development 1997-03, Vol.46 (3), p.419-439
Hauptverfasser: H.J. Looijenga, Leendert, Verkerk, Annemieke J.M.H., de Groot, Nathan, Hochberg, Abraham A., Oosterhuis, J. Wolter
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 439
container_issue 3
container_start_page 419
container_title Molecular reproduction and development
container_volume 46
creator H.J. Looijenga, Leendert
Verkerk, Annemieke J.M.H.
de Groot, Nathan
Hochberg, Abraham A.
Oosterhuis, J. Wolter
description Since our previous review (De Groot and Hochberg, 1993), a large number of studies regarding the role of genomic imprinting in normal development, and in non-neoplastic and neoplastic diseases has been reported. Although a number of very interesting but more general reviews have been published (Feinberg, 1993; Tycko, 1994; Surani, 1994; Ohlsson et al., 1994a; Nicholls, 1994; Langlois, 1994; Efstratiadis, 1994; Barlow, 1994; Brenton et al., 1995; Deal, 1995; Barlow, 1995; Sapienza, 1995; Feinberg et al., 1995; Latham et al., 1995; Franklin et al., 1996; John and Surani, 1996; Leighton et al., 1996), the new data justify an update on genomic imprinting, in particular on H19 and its putative role in normal development and especially neoplastic growth. Data will be discussed which were thought to support the idea that H19 acts as a tumor suppressor gene. We propose that these data are in favor of the hypothesis that H19 acts as an oncofetal gene. We will describe different aspects of H19, including its possible link with the insulin-like growth factor-2 (igf2 for mouse and IGF2 for human).
doi_str_mv 10.1002/(SICI)1098-2795(199703)46:3<419::AID-MRD22>3.0.CO;2-S
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_78836766</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>15918832</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5382-29f15ecd89e50d8489b6209c8c648e26fb5d6bac65f87dead1cbfa0e25aa3c483</originalsourceid><addsrcrecordid>eNqFkEtv1DAURi0EKqXwE5CyQNAuMlw_Yw8PqaSvkQojMaWwu3IcR0rJY4hnaPvvScgoG5C6sa17Px99OoR8oDCjAOzt4WqRLo4oGB2zxMhDakwC_EioOX8vqJnPjxcn8eevJ4x95DOYpct3LF49IvvTj8fDW0AsJPvxlDwL4QYAjNGwR_YMCEqF2idvLqiJyiZq2q62VZT7375q17VvNpFt8qjx7bqyobTPyZPCVsG_2N0H5NvZ6VV6EV8uzxfp8WXsJNcsZqag0rtcGy8h10KbTDEwTjsltGeqyGSuMuuULHSSe5tTlxUWPJPWcic0PyCvR-66a39tfdhgXQbnq8r2VbYBE625SpR6MEiloX2W8amp69oQOl_guitr290jBRxMIw6mcfCGgzccTaNQ2B_UIPam8a_pfgCYLpHhque-3BXYZrXPJ-pObb9_tdvb4GxVdLZxZZhiTAEVMMSux9htWfn7f7o9UO1_zcZBD45HcBk2_m4C2-4nqoQnEr9_OccrqZn4ZChe8z8c_LL7</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>15918832</pqid></control><display><type>article</type><title>H19 in normal development and neoplasia</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>H.J. Looijenga, Leendert ; Verkerk, Annemieke J.M.H. ; de Groot, Nathan ; Hochberg, Abraham A. ; Oosterhuis, J. Wolter</creator><creatorcontrib>H.J. Looijenga, Leendert ; Verkerk, Annemieke J.M.H. ; de Groot, Nathan ; Hochberg, Abraham A. ; Oosterhuis, J. Wolter</creatorcontrib><description>Since our previous review (De Groot and Hochberg, 1993), a large number of studies regarding the role of genomic imprinting in normal development, and in non-neoplastic and neoplastic diseases has been reported. Although a number of very interesting but more general reviews have been published (Feinberg, 1993; Tycko, 1994; Surani, 1994; Ohlsson et al., 1994a; Nicholls, 1994; Langlois, 1994; Efstratiadis, 1994; Barlow, 1994; Brenton et al., 1995; Deal, 1995; Barlow, 1995; Sapienza, 1995; Feinberg et al., 1995; Latham et al., 1995; Franklin et al., 1996; John and Surani, 1996; Leighton et al., 1996), the new data justify an update on genomic imprinting, in particular on H19 and its putative role in normal development and especially neoplastic growth. Data will be discussed which were thought to support the idea that H19 acts as a tumor suppressor gene. We propose that these data are in favor of the hypothesis that H19 acts as an oncofetal gene. We will describe different aspects of H19, including its possible link with the insulin-like growth factor-2 (igf2 for mouse and IGF2 for human).</description><identifier>ISSN: 1040-452X</identifier><identifier>EISSN: 1098-2795</identifier><identifier>DOI: 10.1002/(SICI)1098-2795(199703)46:3&lt;419::AID-MRD22&gt;3.0.CO;2-S</identifier><identifier>PMID: 9041146</identifier><identifier>CODEN: MREDEE</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Animals ; Biological and medical sciences ; Carcinogenesis, carcinogens and anticarcinogens ; General aspects ; Genes, Tumor Suppressor - genetics ; Genomic Imprinting - genetics ; Germinoma - genetics ; Humans ; Insulin-Like Growth Factor II - genetics ; Male ; Medical sciences ; Muscle Proteins - genetics ; Muscle Proteins - isolation &amp; purification ; Neoplasms - genetics ; Pedigree ; RNA, Long Noncoding ; RNA, Untranslated ; Testicular Neoplasms - genetics ; Tumors</subject><ispartof>Molecular reproduction and development, 1997-03, Vol.46 (3), p.419-439</ispartof><rights>Copyright © 1997 Wiley‐Liss, Inc.</rights><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c5382-29f15ecd89e50d8489b6209c8c648e26fb5d6bac65f87dead1cbfa0e25aa3c483</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2F%28SICI%291098-2795%28199703%2946%3A3%3C419%3A%3AAID-MRD22%3E3.0.CO%3B2-S$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2F%28SICI%291098-2795%28199703%2946%3A3%3C419%3A%3AAID-MRD22%3E3.0.CO%3B2-S$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=2601406$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9041146$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>H.J. Looijenga, Leendert</creatorcontrib><creatorcontrib>Verkerk, Annemieke J.M.H.</creatorcontrib><creatorcontrib>de Groot, Nathan</creatorcontrib><creatorcontrib>Hochberg, Abraham A.</creatorcontrib><creatorcontrib>Oosterhuis, J. Wolter</creatorcontrib><title>H19 in normal development and neoplasia</title><title>Molecular reproduction and development</title><addtitle>Mol. Reprod. Dev</addtitle><description>Since our previous review (De Groot and Hochberg, 1993), a large number of studies regarding the role of genomic imprinting in normal development, and in non-neoplastic and neoplastic diseases has been reported. Although a number of very interesting but more general reviews have been published (Feinberg, 1993; Tycko, 1994; Surani, 1994; Ohlsson et al., 1994a; Nicholls, 1994; Langlois, 1994; Efstratiadis, 1994; Barlow, 1994; Brenton et al., 1995; Deal, 1995; Barlow, 1995; Sapienza, 1995; Feinberg et al., 1995; Latham et al., 1995; Franklin et al., 1996; John and Surani, 1996; Leighton et al., 1996), the new data justify an update on genomic imprinting, in particular on H19 and its putative role in normal development and especially neoplastic growth. Data will be discussed which were thought to support the idea that H19 acts as a tumor suppressor gene. We propose that these data are in favor of the hypothesis that H19 acts as an oncofetal gene. We will describe different aspects of H19, including its possible link with the insulin-like growth factor-2 (igf2 for mouse and IGF2 for human).</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Carcinogenesis, carcinogens and anticarcinogens</subject><subject>General aspects</subject><subject>Genes, Tumor Suppressor - genetics</subject><subject>Genomic Imprinting - genetics</subject><subject>Germinoma - genetics</subject><subject>Humans</subject><subject>Insulin-Like Growth Factor II - genetics</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Muscle Proteins - genetics</subject><subject>Muscle Proteins - isolation &amp; purification</subject><subject>Neoplasms - genetics</subject><subject>Pedigree</subject><subject>RNA, Long Noncoding</subject><subject>RNA, Untranslated</subject><subject>Testicular Neoplasms - genetics</subject><subject>Tumors</subject><issn>1040-452X</issn><issn>1098-2795</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtv1DAURi0EKqXwE5CyQNAuMlw_Yw8PqaSvkQojMaWwu3IcR0rJY4hnaPvvScgoG5C6sa17Px99OoR8oDCjAOzt4WqRLo4oGB2zxMhDakwC_EioOX8vqJnPjxcn8eevJ4x95DOYpct3LF49IvvTj8fDW0AsJPvxlDwL4QYAjNGwR_YMCEqF2idvLqiJyiZq2q62VZT7375q17VvNpFt8qjx7bqyobTPyZPCVsG_2N0H5NvZ6VV6EV8uzxfp8WXsJNcsZqag0rtcGy8h10KbTDEwTjsltGeqyGSuMuuULHSSe5tTlxUWPJPWcic0PyCvR-66a39tfdhgXQbnq8r2VbYBE625SpR6MEiloX2W8amp69oQOl_guitr290jBRxMIw6mcfCGgzccTaNQ2B_UIPam8a_pfgCYLpHhque-3BXYZrXPJ-pObb9_tdvb4GxVdLZxZZhiTAEVMMSux9htWfn7f7o9UO1_zcZBD45HcBk2_m4C2-4nqoQnEr9_OccrqZn4ZChe8z8c_LL7</recordid><startdate>199703</startdate><enddate>199703</enddate><creator>H.J. Looijenga, Leendert</creator><creator>Verkerk, Annemieke J.M.H.</creator><creator>de Groot, Nathan</creator><creator>Hochberg, Abraham A.</creator><creator>Oosterhuis, J. Wolter</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>199703</creationdate><title>H19 in normal development and neoplasia</title><author>H.J. Looijenga, Leendert ; Verkerk, Annemieke J.M.H. ; de Groot, Nathan ; Hochberg, Abraham A. ; Oosterhuis, J. Wolter</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5382-29f15ecd89e50d8489b6209c8c648e26fb5d6bac65f87dead1cbfa0e25aa3c483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Carcinogenesis, carcinogens and anticarcinogens</topic><topic>General aspects</topic><topic>Genes, Tumor Suppressor - genetics</topic><topic>Genomic Imprinting - genetics</topic><topic>Germinoma - genetics</topic><topic>Humans</topic><topic>Insulin-Like Growth Factor II - genetics</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Muscle Proteins - genetics</topic><topic>Muscle Proteins - isolation &amp; purification</topic><topic>Neoplasms - genetics</topic><topic>Pedigree</topic><topic>RNA, Long Noncoding</topic><topic>RNA, Untranslated</topic><topic>Testicular Neoplasms - genetics</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>H.J. Looijenga, Leendert</creatorcontrib><creatorcontrib>Verkerk, Annemieke J.M.H.</creatorcontrib><creatorcontrib>de Groot, Nathan</creatorcontrib><creatorcontrib>Hochberg, Abraham A.</creatorcontrib><creatorcontrib>Oosterhuis, J. Wolter</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Molecular reproduction and development</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>H.J. Looijenga, Leendert</au><au>Verkerk, Annemieke J.M.H.</au><au>de Groot, Nathan</au><au>Hochberg, Abraham A.</au><au>Oosterhuis, J. Wolter</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>H19 in normal development and neoplasia</atitle><jtitle>Molecular reproduction and development</jtitle><addtitle>Mol. Reprod. Dev</addtitle><date>1997-03</date><risdate>1997</risdate><volume>46</volume><issue>3</issue><spage>419</spage><epage>439</epage><pages>419-439</pages><issn>1040-452X</issn><eissn>1098-2795</eissn><coden>MREDEE</coden><abstract>Since our previous review (De Groot and Hochberg, 1993), a large number of studies regarding the role of genomic imprinting in normal development, and in non-neoplastic and neoplastic diseases has been reported. Although a number of very interesting but more general reviews have been published (Feinberg, 1993; Tycko, 1994; Surani, 1994; Ohlsson et al., 1994a; Nicholls, 1994; Langlois, 1994; Efstratiadis, 1994; Barlow, 1994; Brenton et al., 1995; Deal, 1995; Barlow, 1995; Sapienza, 1995; Feinberg et al., 1995; Latham et al., 1995; Franklin et al., 1996; John and Surani, 1996; Leighton et al., 1996), the new data justify an update on genomic imprinting, in particular on H19 and its putative role in normal development and especially neoplastic growth. Data will be discussed which were thought to support the idea that H19 acts as a tumor suppressor gene. We propose that these data are in favor of the hypothesis that H19 acts as an oncofetal gene. We will describe different aspects of H19, including its possible link with the insulin-like growth factor-2 (igf2 for mouse and IGF2 for human).</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>9041146</pmid><doi>10.1002/(SICI)1098-2795(199703)46:3&lt;419::AID-MRD22&gt;3.0.CO;2-S</doi><tpages>21</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1040-452X
ispartof Molecular reproduction and development, 1997-03, Vol.46 (3), p.419-439
issn 1040-452X
1098-2795
language eng
recordid cdi_proquest_miscellaneous_78836766
source MEDLINE; Access via Wiley Online Library
subjects Animals
Biological and medical sciences
Carcinogenesis, carcinogens and anticarcinogens
General aspects
Genes, Tumor Suppressor - genetics
Genomic Imprinting - genetics
Germinoma - genetics
Humans
Insulin-Like Growth Factor II - genetics
Male
Medical sciences
Muscle Proteins - genetics
Muscle Proteins - isolation & purification
Neoplasms - genetics
Pedigree
RNA, Long Noncoding
RNA, Untranslated
Testicular Neoplasms - genetics
Tumors
title H19 in normal development and neoplasia
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T18%3A44%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=H19%20in%20normal%20development%20and%20neoplasia&rft.jtitle=Molecular%20reproduction%20and%20development&rft.au=H.J.%20Looijenga,%20Leendert&rft.date=1997-03&rft.volume=46&rft.issue=3&rft.spage=419&rft.epage=439&rft.pages=419-439&rft.issn=1040-452X&rft.eissn=1098-2795&rft.coden=MREDEE&rft_id=info:doi/10.1002/(SICI)1098-2795(199703)46:3%3C419::AID-MRD22%3E3.0.CO;2-S&rft_dat=%3Cproquest_cross%3E15918832%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=15918832&rft_id=info:pmid/9041146&rfr_iscdi=true