Counseling for Low Maternal Serum Alpha-Fetoprotein Should Emphasize All Chromosome Anomalies, Not Just Down Syndrome

In common usage, a low maternal serum alpha-fetoprotein (MSAFP) value is associated with an increased risk of Down syndrome. We have performed amniocenteses for the indication of age-adjusted low MSAFP in 1154 patients and found 13 chromosomally abnormal conceptions. Autosomal trisomies were detecte...

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Veröffentlicht in:	Obstetrics and gynecology (New York. 1953) 1989-02, Vol.73 (2), p.271-274
Hauptverfasser:	DRUGAN, ARIE, DVORIN, ELENA, KOPPITCH, FREDERICK C, GREB, ANNE, KRIVCHENIA, ERIC L, EVANS, MARK I
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult alpha-Fetoproteins - analysis Amniocentesis Biological and medical sciences Chromosome Aberrations - diagnosis Chromosome Disorders Down Syndrome - diagnosis Female Genetic Counseling Gynecology. Andrology. Obstetrics Humans Management. Prenatal diagnosis Maternal Age Medical sciences Pregnancy Pregnancy, High-Risk Pregnancy. Fetus. Placenta Risk Factors
Online-Zugang:	Volltext
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