Infection of human cells by an endogenous retrovirus of pigs

The possible use of pig organs and tissues as xenografts in humans is actively being considered in biomedical research. We therefore examined whether pig endogenous retrovirus (PERV) genomes can be infectiously transmitted to human cells in culture. Two pig kidney cell lines spontaneously produce C-...

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Veröffentlicht in:	Nature medicine 1997-03, Vol.3 (3), p.282-286
Hauptverfasser:	Patience, Clive, Takeuchi, Yasuhiro, Weiss, Robin A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Cell Line Coculture Techniques Gammaretrovirus - genetics Genome, Viral Humans Kidney - virology Molecular Sequence Data Retroviridae Infections - transmission Swine Tumor Virus Infections - transmission
Online-Zugang:	Volltext
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