Altered Cardiac Mechanism and Sarcoplasmic Reticulum Function in Pressure Overload-induced Cardiac Hypertrophy in Rats

Cardiac sarcoplasmic reticulum (SR) sequesters Ca2+and plays a crucial role in the regulation of intracellular Ca2+. Its functional properties are central to the excitation–contraction (E–C) cycle of cardiac muscle. In this study, we examined the hypothesis that alterations in SR function occur duri...

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