Presence of IL-1 receptors on human and murine neutrophils. Relevance to IL-1-mediated effects in inflammation

Inflammatory responses are characterized by the infiltration of polymorphonuclear neutrophils (PMN) at the involved site. IL-1 may have an important role in mediating this response, but whether IL-1 acts directly on PMN is controversial. In this study, we examined PMN for the presence of IL-1R and d...

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Veröffentlicht in:	The Journal of immunology (1950) 1989-01, Vol.142 (2), p.537-542
Hauptverfasser:	Parker, KP, Benjamin, WR, Kaffka, KL, Kilian, PL
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Animals Ascitic Fluid Binding, Competitive Biological and medical sciences Caseins - administration & dosage Cell Movement - drug effects Cell Separation Female Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Hydrogen-Ion Concentration Immunobiology Inflammation - metabolism Inflammation - pathology Interleukin-1 - metabolism Interleukin-1 - physiology Kinetics Lymphokines, interleukins ( function, expression) Mice Mice, Inbred C57BL Neutrophils - metabolism Neutrophils - physiology Peptide Fragments - administration & dosage Receptors, Immunologic - analysis Receptors, Interleukin-1 Regulatory factors and their cellular receptors Thioglycolates
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