Immunodeficiency in patients with hemophilia: An underlying deficiency and lack of correlation with factor replacement therapy or exposure to human immunodeficiency virus

Nineteen patients with hemophilia, five of whom were classified as untreated, were immunologically evaluated by the measurement of cell surface markers, natural killer cell activity, mitogenic responses, polyclonal immunoglobulin production, and serologic evidence of human immunodeficiency virus inf...

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