Plasma ascorbic acid level and erythrocyte fragility in preeclampsia and eclampsia
An imbalance between oxidants and antioxidants in the circulation is blamed to cause preeclampsia and eclampsia. In this study plasma ascorbic acid level was analysed in 13 eclamptic, 14 mild preeclamptic, 12 severe preeclamptic and 20 uncomplicated pregnancies to see whether there is any correlatio...
Gespeichert in:
| Veröffentlicht in: | European journal of obstetrics & gynecology and reproductive biology 1997, Vol.71 (1), p.35-40 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 40 |
|---|---|
| container_issue | 1 |
| container_start_page | 35 |
| container_title | European journal of obstetrics & gynecology and reproductive biology |
| container_volume | 71 |
| creator | Ozan, Hakan Esmer, Ahmet Kolsal, Nedret Çopur, Ömer Utku Ediz, Bülent |
| description | An imbalance between oxidants and antioxidants in the circulation is blamed to cause preeclampsia and eclampsia. In this study plasma ascorbic acid level was analysed in 13 eclamptic, 14 mild preeclamptic, 12 severe preeclamptic and 20 uncomplicated pregnancies to see whether there is any correlation with blood pressure, proteinuria, serum triglyceride level, erythrocyte fragility and leukocyte count. Plasma ascorbic acid level was normal and had no significant difference among the groups. Fasting serum triglyceride level was significantly higher in the study group than in the control group but it did not differ among the three study groups. Erythrocyte fragility was found to be increased in all three study groups. Blood leukocyte count was increased in the study groups, especially in the eclampsia group. However, plasma ascorbic acid level and erythrocyte fragility were found to have no significant correlation with blood pressure and proteinuria. It was concluded that though the ascorbic acid levels were normal in both the study and the control groups, erythrocyte fragility increased probably due to an elevation in peroxide and free radical levels in preeclampsia and eclampsia groups, but without any correlation with the severity of the clinical picture. |
| doi_str_mv | 10.1016/S0301-2115(96)02613-9 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_78824292</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0301211596026139</els_id><sourcerecordid>78824292</sourcerecordid><originalsourceid>FETCH-LOGICAL-c389t-e0394679e75b0b097ac41b70e84419a78f4dcff3efc936e056086c7e1edcedf73</originalsourceid><addsrcrecordid>eNqFkEtLxDAQgIMo6_r4CQs9iOihmjRN0pxEFl-woPg4hzSdaiRt16S70H9vd1v36lyGYb6ZST6EZgRfEUz49RummMQJIexC8kuccEJjuYemJBNJLDhL99F0hxyioxC-cR-UygmaSEyJZNkUvb44HSod6WAan1sTaWOLyMEaXKTrIgLftV--MV0LUen1p3W27SJbR0sPYJyulsHqgfyrTtBBqV2A0zEfo4_7u_f5Y7x4fnia3y5iQzPZxoCpTLmQIFiOcyyFNinJBYYsTYnUIivTwpQlhdJIygEzjjNuBBAoDBSloMfofNi79M3PCkKrKhsMOKdraFZBiSxL0kQmPcgG0PgmBA-lWnpbad8pgtXGpdq6VBtRSnK1dalkPzcbD6zyCord1Civ75-N_d6edr2e2tiwwxLGBWOb8zcDBr2MtQWvgrFQ95-wHkyrisb-85Bf0aOQ7A</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>78824292</pqid></control><display><type>article</type><title>Plasma ascorbic acid level and erythrocyte fragility in preeclampsia and eclampsia</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Ozan, Hakan ; Esmer, Ahmet ; Kolsal, Nedret ; Çopur, Ömer Utku ; Ediz, Bülent</creator><creatorcontrib>Ozan, Hakan ; Esmer, Ahmet ; Kolsal, Nedret ; Çopur, Ömer Utku ; Ediz, Bülent</creatorcontrib><description>An imbalance between oxidants and antioxidants in the circulation is blamed to cause preeclampsia and eclampsia. In this study plasma ascorbic acid level was analysed in 13 eclamptic, 14 mild preeclamptic, 12 severe preeclamptic and 20 uncomplicated pregnancies to see whether there is any correlation with blood pressure, proteinuria, serum triglyceride level, erythrocyte fragility and leukocyte count. Plasma ascorbic acid level was normal and had no significant difference among the groups. Fasting serum triglyceride level was significantly higher in the study group than in the control group but it did not differ among the three study groups. Erythrocyte fragility was found to be increased in all three study groups. Blood leukocyte count was increased in the study groups, especially in the eclampsia group. However, plasma ascorbic acid level and erythrocyte fragility were found to have no significant correlation with blood pressure and proteinuria. It was concluded that though the ascorbic acid levels were normal in both the study and the control groups, erythrocyte fragility increased probably due to an elevation in peroxide and free radical levels in preeclampsia and eclampsia groups, but without any correlation with the severity of the clinical picture.</description><identifier>ISSN: 0301-2115</identifier><identifier>EISSN: 1872-7654</identifier><identifier>DOI: 10.1016/S0301-2115(96)02613-9</identifier><identifier>PMID: 9031958</identifier><identifier>CODEN: EOGRAL</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Adult ; Apgar Score ; Ascorbic acid ; Ascorbic Acid - blood ; Biological and medical sciences ; Blood Pressure ; Diseases of mother, fetus and pregnancy ; Eclampsia ; Eclampsia - blood ; Eclampsia - physiopathology ; Erythrocyte fragility ; Female ; Gestational Age ; Gynecology. Andrology. Obstetrics ; Humans ; Leukocyte Count ; Medical sciences ; Osmotic Fragility ; Pre-Eclampsia - blood ; Pre-Eclampsia - physiopathology ; Preeclampsia ; Pregnancy ; Pregnancy. Fetus. Placenta ; Triglycerides - blood</subject><ispartof>European journal of obstetrics & gynecology and reproductive biology, 1997, Vol.71 (1), p.35-40</ispartof><rights>1997</rights><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c389t-e0394679e75b0b097ac41b70e84419a78f4dcff3efc936e056086c7e1edcedf73</citedby><cites>FETCH-LOGICAL-c389t-e0394679e75b0b097ac41b70e84419a78f4dcff3efc936e056086c7e1edcedf73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0301211596026139$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,4010,27900,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2567552$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9031958$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ozan, Hakan</creatorcontrib><creatorcontrib>Esmer, Ahmet</creatorcontrib><creatorcontrib>Kolsal, Nedret</creatorcontrib><creatorcontrib>Çopur, Ömer Utku</creatorcontrib><creatorcontrib>Ediz, Bülent</creatorcontrib><title>Plasma ascorbic acid level and erythrocyte fragility in preeclampsia and eclampsia</title><title>European journal of obstetrics & gynecology and reproductive biology</title><addtitle>Eur J Obstet Gynecol Reprod Biol</addtitle><description>An imbalance between oxidants and antioxidants in the circulation is blamed to cause preeclampsia and eclampsia. In this study plasma ascorbic acid level was analysed in 13 eclamptic, 14 mild preeclamptic, 12 severe preeclamptic and 20 uncomplicated pregnancies to see whether there is any correlation with blood pressure, proteinuria, serum triglyceride level, erythrocyte fragility and leukocyte count. Plasma ascorbic acid level was normal and had no significant difference among the groups. Fasting serum triglyceride level was significantly higher in the study group than in the control group but it did not differ among the three study groups. Erythrocyte fragility was found to be increased in all three study groups. Blood leukocyte count was increased in the study groups, especially in the eclampsia group. However, plasma ascorbic acid level and erythrocyte fragility were found to have no significant correlation with blood pressure and proteinuria. It was concluded that though the ascorbic acid levels were normal in both the study and the control groups, erythrocyte fragility increased probably due to an elevation in peroxide and free radical levels in preeclampsia and eclampsia groups, but without any correlation with the severity of the clinical picture.</description><subject>Adult</subject><subject>Apgar Score</subject><subject>Ascorbic acid</subject><subject>Ascorbic Acid - blood</subject><subject>Biological and medical sciences</subject><subject>Blood Pressure</subject><subject>Diseases of mother, fetus and pregnancy</subject><subject>Eclampsia</subject><subject>Eclampsia - blood</subject><subject>Eclampsia - physiopathology</subject><subject>Erythrocyte fragility</subject><subject>Female</subject><subject>Gestational Age</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Leukocyte Count</subject><subject>Medical sciences</subject><subject>Osmotic Fragility</subject><subject>Pre-Eclampsia - blood</subject><subject>Pre-Eclampsia - physiopathology</subject><subject>Preeclampsia</subject><subject>Pregnancy</subject><subject>Pregnancy. Fetus. Placenta</subject><subject>Triglycerides - blood</subject><issn>0301-2115</issn><issn>1872-7654</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLxDAQgIMo6_r4CQs9iOihmjRN0pxEFl-woPg4hzSdaiRt16S70H9vd1v36lyGYb6ZST6EZgRfEUz49RummMQJIexC8kuccEJjuYemJBNJLDhL99F0hxyioxC-cR-UygmaSEyJZNkUvb44HSod6WAan1sTaWOLyMEaXKTrIgLftV--MV0LUen1p3W27SJbR0sPYJyulsHqgfyrTtBBqV2A0zEfo4_7u_f5Y7x4fnia3y5iQzPZxoCpTLmQIFiOcyyFNinJBYYsTYnUIivTwpQlhdJIygEzjjNuBBAoDBSloMfofNi79M3PCkKrKhsMOKdraFZBiSxL0kQmPcgG0PgmBA-lWnpbad8pgtXGpdq6VBtRSnK1dalkPzcbD6zyCord1Civ75-N_d6edr2e2tiwwxLGBWOb8zcDBr2MtQWvgrFQ95-wHkyrisb-85Bf0aOQ7A</recordid><startdate>1997</startdate><enddate>1997</enddate><creator>Ozan, Hakan</creator><creator>Esmer, Ahmet</creator><creator>Kolsal, Nedret</creator><creator>Çopur, Ömer Utku</creator><creator>Ediz, Bülent</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1997</creationdate><title>Plasma ascorbic acid level and erythrocyte fragility in preeclampsia and eclampsia</title><author>Ozan, Hakan ; Esmer, Ahmet ; Kolsal, Nedret ; Çopur, Ömer Utku ; Ediz, Bülent</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-e0394679e75b0b097ac41b70e84419a78f4dcff3efc936e056086c7e1edcedf73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adult</topic><topic>Apgar Score</topic><topic>Ascorbic acid</topic><topic>Ascorbic Acid - blood</topic><topic>Biological and medical sciences</topic><topic>Blood Pressure</topic><topic>Diseases of mother, fetus and pregnancy</topic><topic>Eclampsia</topic><topic>Eclampsia - blood</topic><topic>Eclampsia - physiopathology</topic><topic>Erythrocyte fragility</topic><topic>Female</topic><topic>Gestational Age</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Leukocyte Count</topic><topic>Medical sciences</topic><topic>Osmotic Fragility</topic><topic>Pre-Eclampsia - blood</topic><topic>Pre-Eclampsia - physiopathology</topic><topic>Preeclampsia</topic><topic>Pregnancy</topic><topic>Pregnancy. Fetus. Placenta</topic><topic>Triglycerides - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ozan, Hakan</creatorcontrib><creatorcontrib>Esmer, Ahmet</creatorcontrib><creatorcontrib>Kolsal, Nedret</creatorcontrib><creatorcontrib>Çopur, Ömer Utku</creatorcontrib><creatorcontrib>Ediz, Bülent</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of obstetrics & gynecology and reproductive biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ozan, Hakan</au><au>Esmer, Ahmet</au><au>Kolsal, Nedret</au><au>Çopur, Ömer Utku</au><au>Ediz, Bülent</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Plasma ascorbic acid level and erythrocyte fragility in preeclampsia and eclampsia</atitle><jtitle>European journal of obstetrics & gynecology and reproductive biology</jtitle><addtitle>Eur J Obstet Gynecol Reprod Biol</addtitle><date>1997</date><risdate>1997</risdate><volume>71</volume><issue>1</issue><spage>35</spage><epage>40</epage><pages>35-40</pages><issn>0301-2115</issn><eissn>1872-7654</eissn><coden>EOGRAL</coden><abstract>An imbalance between oxidants and antioxidants in the circulation is blamed to cause preeclampsia and eclampsia. In this study plasma ascorbic acid level was analysed in 13 eclamptic, 14 mild preeclamptic, 12 severe preeclamptic and 20 uncomplicated pregnancies to see whether there is any correlation with blood pressure, proteinuria, serum triglyceride level, erythrocyte fragility and leukocyte count. Plasma ascorbic acid level was normal and had no significant difference among the groups. Fasting serum triglyceride level was significantly higher in the study group than in the control group but it did not differ among the three study groups. Erythrocyte fragility was found to be increased in all three study groups. Blood leukocyte count was increased in the study groups, especially in the eclampsia group. However, plasma ascorbic acid level and erythrocyte fragility were found to have no significant correlation with blood pressure and proteinuria. It was concluded that though the ascorbic acid levels were normal in both the study and the control groups, erythrocyte fragility increased probably due to an elevation in peroxide and free radical levels in preeclampsia and eclampsia groups, but without any correlation with the severity of the clinical picture.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>9031958</pmid><doi>10.1016/S0301-2115(96)02613-9</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0301-2115 |
| ispartof | European journal of obstetrics & gynecology and reproductive biology, 1997, Vol.71 (1), p.35-40 |
| issn | 0301-2115 1872-7654 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_78824292 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Apgar Score Ascorbic acid Ascorbic Acid - blood Biological and medical sciences Blood Pressure Diseases of mother, fetus and pregnancy Eclampsia Eclampsia - blood Eclampsia - physiopathology Erythrocyte fragility Female Gestational Age Gynecology. Andrology. Obstetrics Humans Leukocyte Count Medical sciences Osmotic Fragility Pre-Eclampsia - blood Pre-Eclampsia - physiopathology Preeclampsia Pregnancy Pregnancy. Fetus. Placenta Triglycerides - blood |
| title | Plasma ascorbic acid level and erythrocyte fragility in preeclampsia and eclampsia |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T01%3A41%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Plasma%20ascorbic%20acid%20level%20and%20erythrocyte%20fragility%20in%20preeclampsia%20and%20eclampsia&rft.jtitle=European%20journal%20of%20obstetrics%20&%20gynecology%20and%20reproductive%20biology&rft.au=Ozan,%20Hakan&rft.date=1997&rft.volume=71&rft.issue=1&rft.spage=35&rft.epage=40&rft.pages=35-40&rft.issn=0301-2115&rft.eissn=1872-7654&rft.coden=EOGRAL&rft_id=info:doi/10.1016/S0301-2115(96)02613-9&rft_dat=%3Cproquest_cross%3E78824292%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=78824292&rft_id=info:pmid/9031958&rft_els_id=S0301211596026139&rfr_iscdi=true |