Inhibition of monocyte and polymorphonuclear granulocyte immune phagocytosis by monoclonal antibodies specific for FcγRI, II and III

We tested two Fc gamma receptor I (Fc gamma RI); six Fc gamma RII; and six Fc gamma RIII-specific monoclonal antibodies (mAb) for their capacity to inhibit monocyte and polymorphonuclear granulocyte (PMN) immune phagocytosis which is mediated by Fc gamma R. We used human red blood cells (rbc) coated...

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Veröffentlicht in:	Annals of hematology 1997-01, Vol.74 (1), p.15-22
Hauptverfasser:	FLESCH, B. K, ACHTERT, G, NEPPERT, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Antibodies, Monoclonal - pharmacology Antibody Specificity Biological and medical sciences Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunobiology Leukocytes - immunology Leukocytes, Mononuclear - immunology Mice Myeloid cells: ontogeny, maturation, markers, receptors Neutrophils - immunology Phagocytosis - immunology Phenotype Polynuclears Receptors, IgG - genetics Receptors, IgG - immunology
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