Accelerated Gastric Emptying in Hypertensive Subjects
The phenomenon of accelerated gastric emptying has been previously reported in two conditions that are considered to be part of the insulin-resistance syndrome: namely, noninsulin-dependent diabetes (NIDDM) and increased body mass index (BMI). No previous studies have assessed the rate of gastric em...
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| Veröffentlicht in: | The Journal of nuclear medicine (1978) 1997-02, Vol.38 (2), p.207-211 |
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| container_title | The Journal of nuclear medicine (1978) |
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| creator | Phillips, William T Salman, Umber A McMahan, C. Alex Schwartz, Joyce G |
| description | The phenomenon of accelerated gastric emptying has been previously reported in two conditions that are considered to be part of the insulin-resistance syndrome: namely, noninsulin-dependent diabetes (NIDDM) and increased body mass index (BMI). No previous studies have assessed the rate of gastric emptying in patients with essential hypertension, another disease considered to be part of the insulin-resistance syndrome.
Scintigraphic gastric emptying studies were performed on nine hypertensive subjects and on nine sex-, age-, ethnicity and BMI-matched controls.
Subjects with hypertension had significantly more rapid gastric half-emptying times (gastric T50) (40.0 +/- 6.9 min versus 56.6 +/- 3.7 min, p = 0.02) than controls. There was an inverse relationship between average glucose during the first 30 min and 60 min of the oral glucose tolerance test with the gastric half-emptying time (Spearman rank correlation coefficient rs = -0.64, p = 0.0045 and rs = -0.48, p = 0.0428, respectively).
The occurrence of accelerated gastric emptying in hypertensive subjects, in addition to that previously reported in subjects with NIDDM or increased BMI, suggests the possibility that accelerated gastric emptying may be a common finding in insulin resistant states. |
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Scintigraphic gastric emptying studies were performed on nine hypertensive subjects and on nine sex-, age-, ethnicity and BMI-matched controls.
Subjects with hypertension had significantly more rapid gastric half-emptying times (gastric T50) (40.0 +/- 6.9 min versus 56.6 +/- 3.7 min, p = 0.02) than controls. There was an inverse relationship between average glucose during the first 30 min and 60 min of the oral glucose tolerance test with the gastric half-emptying time (Spearman rank correlation coefficient rs = -0.64, p = 0.0045 and rs = -0.48, p = 0.0428, respectively).
The occurrence of accelerated gastric emptying in hypertensive subjects, in addition to that previously reported in subjects with NIDDM or increased BMI, suggests the possibility that accelerated gastric emptying may be a common finding in insulin resistant states.</description><identifier>ISSN: 0161-5505</identifier><identifier>EISSN: 1535-5667</identifier><identifier>PMID: 9025737</identifier><identifier>CODEN: JNMEAQ</identifier><language>eng</language><publisher>Reston, VA: Soc Nuclear Med</publisher><subject>Adult ; Biological and medical sciences ; Blood Glucose - metabolism ; Body Mass Index ; Digestion. Liver. Biliary tract. Spleen. Pancreas ; Female ; Functional investigation of the digestive system ; Gastric Emptying - physiology ; Glucose Tolerance Test ; Humans ; Hypertension - blood ; Hypertension - physiopathology ; Insulin - blood ; Insulin Resistance - physiology ; Investigative techniques, diagnostic techniques (general aspects) ; Male ; Medical sciences ; Radionuclide investigations ; Technetium Tc 99m Sulfur Colloid</subject><ispartof>The Journal of nuclear medicine (1978), 1997-02, Vol.38 (2), p.207-211</ispartof><rights>1997 INIST-CNRS</rights><rights>Copyright Society of Nuclear Medicine Feb 1997</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2574776$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9025737$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Phillips, William T</creatorcontrib><creatorcontrib>Salman, Umber A</creatorcontrib><creatorcontrib>McMahan, C. Alex</creatorcontrib><creatorcontrib>Schwartz, Joyce G</creatorcontrib><title>Accelerated Gastric Emptying in Hypertensive Subjects</title><title>The Journal of nuclear medicine (1978)</title><addtitle>J Nucl Med</addtitle><description>The phenomenon of accelerated gastric emptying has been previously reported in two conditions that are considered to be part of the insulin-resistance syndrome: namely, noninsulin-dependent diabetes (NIDDM) and increased body mass index (BMI). No previous studies have assessed the rate of gastric emptying in patients with essential hypertension, another disease considered to be part of the insulin-resistance syndrome.
Scintigraphic gastric emptying studies were performed on nine hypertensive subjects and on nine sex-, age-, ethnicity and BMI-matched controls.
Subjects with hypertension had significantly more rapid gastric half-emptying times (gastric T50) (40.0 +/- 6.9 min versus 56.6 +/- 3.7 min, p = 0.02) than controls. There was an inverse relationship between average glucose during the first 30 min and 60 min of the oral glucose tolerance test with the gastric half-emptying time (Spearman rank correlation coefficient rs = -0.64, p = 0.0045 and rs = -0.48, p = 0.0428, respectively).
The occurrence of accelerated gastric emptying in hypertensive subjects, in addition to that previously reported in subjects with NIDDM or increased BMI, suggests the possibility that accelerated gastric emptying may be a common finding in insulin resistant states.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Blood Glucose - metabolism</subject><subject>Body Mass Index</subject><subject>Digestion. Liver. Biliary tract. Spleen. Pancreas</subject><subject>Female</subject><subject>Functional investigation of the digestive system</subject><subject>Gastric Emptying - physiology</subject><subject>Glucose Tolerance Test</subject><subject>Humans</subject><subject>Hypertension - blood</subject><subject>Hypertension - physiopathology</subject><subject>Insulin - blood</subject><subject>Insulin Resistance - physiology</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Radionuclide investigations</subject><subject>Technetium Tc 99m Sulfur Colloid</subject><issn>0161-5505</issn><issn>1535-5667</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpdkF1LwzAUhoMoc05_glBEvCucJstHL8eYmzDwQr0OaXqypbTdTFpl_96KRcGrA-_78PJwzsg044ynXAh5TqaQiSzlHPgluYqxAgChlJqQSQ6USyanhC-sxRqD6bBM1iZ2wdtk1Ry7k293iW-TzemIocM2-g9MXvqiQtvFa3LhTB3xZrwz8va4el1u0u3z-mm52KZ7mrMuVRaoMULlOSusLVC4khtAIfmQmjKXAixTziEKq1xmGZhyLsBQdMAdc2xGHn52j-Hw3mPsdOPj4FubFg991FIpChmwAbz7B1aHPrSDm6ZZTiHP5jBAtyPUFw2W-hh8Y8JJj88Y-vuxN9Ga2gXTWh9_sQGaSyn-pPZ-t__0AXXb2xpN-N6s2oYpTTUFyb4A2Yh1vw</recordid><startdate>19970201</startdate><enddate>19970201</enddate><creator>Phillips, William T</creator><creator>Salman, Umber A</creator><creator>McMahan, C. 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Alex ; Schwartz, Joyce G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h293t-8c02aa68993bccbe6fd5a0e675aa6ad9760c38ffee6c8f1c30ad460a2ef05f3f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Blood Glucose - metabolism</topic><topic>Body Mass Index</topic><topic>Digestion. Liver. Biliary tract. Spleen. Pancreas</topic><topic>Female</topic><topic>Functional investigation of the digestive system</topic><topic>Gastric Emptying - physiology</topic><topic>Glucose Tolerance Test</topic><topic>Humans</topic><topic>Hypertension - blood</topic><topic>Hypertension - physiopathology</topic><topic>Insulin - blood</topic><topic>Insulin Resistance - physiology</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Radionuclide investigations</topic><topic>Technetium Tc 99m Sulfur Colloid</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Phillips, William T</creatorcontrib><creatorcontrib>Salman, Umber A</creatorcontrib><creatorcontrib>McMahan, C. 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Alex</au><au>Schwartz, Joyce G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Accelerated Gastric Emptying in Hypertensive Subjects</atitle><jtitle>The Journal of nuclear medicine (1978)</jtitle><addtitle>J Nucl Med</addtitle><date>1997-02-01</date><risdate>1997</risdate><volume>38</volume><issue>2</issue><spage>207</spage><epage>211</epage><pages>207-211</pages><issn>0161-5505</issn><eissn>1535-5667</eissn><coden>JNMEAQ</coden><abstract>The phenomenon of accelerated gastric emptying has been previously reported in two conditions that are considered to be part of the insulin-resistance syndrome: namely, noninsulin-dependent diabetes (NIDDM) and increased body mass index (BMI). No previous studies have assessed the rate of gastric emptying in patients with essential hypertension, another disease considered to be part of the insulin-resistance syndrome.
Scintigraphic gastric emptying studies were performed on nine hypertensive subjects and on nine sex-, age-, ethnicity and BMI-matched controls.
Subjects with hypertension had significantly more rapid gastric half-emptying times (gastric T50) (40.0 +/- 6.9 min versus 56.6 +/- 3.7 min, p = 0.02) than controls. There was an inverse relationship between average glucose during the first 30 min and 60 min of the oral glucose tolerance test with the gastric half-emptying time (Spearman rank correlation coefficient rs = -0.64, p = 0.0045 and rs = -0.48, p = 0.0428, respectively).
The occurrence of accelerated gastric emptying in hypertensive subjects, in addition to that previously reported in subjects with NIDDM or increased BMI, suggests the possibility that accelerated gastric emptying may be a common finding in insulin resistant states.</abstract><cop>Reston, VA</cop><pub>Soc Nuclear Med</pub><pmid>9025737</pmid><tpages>5</tpages></addata></record> |
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| ispartof | The Journal of nuclear medicine (1978), 1997-02, Vol.38 (2), p.207-211 |
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| subjects | Adult Biological and medical sciences Blood Glucose - metabolism Body Mass Index Digestion. Liver. Biliary tract. Spleen. Pancreas Female Functional investigation of the digestive system Gastric Emptying - physiology Glucose Tolerance Test Humans Hypertension - blood Hypertension - physiopathology Insulin - blood Insulin Resistance - physiology Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Radionuclide investigations Technetium Tc 99m Sulfur Colloid |
| title | Accelerated Gastric Emptying in Hypertensive Subjects |
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