Estrogen Replacement Therapy and Exercise Performance in Postmenopausal Women With Coronary Artery Disease

We treated 10 postmenopausal women with stable angina, positive exercise test, and documented coronary artery disease with oral conjugated equine estrogen (0.625 mg/day of Premarin) or placebo for 4 weeks, in random order, with crossover after a 4-week washout period. Exercise tests, performed after...

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Veröffentlicht in:The American journal of cardiology 1997-01, Vol.79 (1), p.87-89
Hauptverfasser: Sbarouni, Eftihia, Kyriakides, Zenon S, Nikolaou, Nikolaos, Kremastinos, Dimitrios Th
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container_title The American journal of cardiology
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creator Sbarouni, Eftihia
Kyriakides, Zenon S
Nikolaou, Nikolaos
Kremastinos, Dimitrios Th
description We treated 10 postmenopausal women with stable angina, positive exercise test, and documented coronary artery disease with oral conjugated equine estrogen (0.625 mg/day of Premarin) or placebo for 4 weeks, in random order, with crossover after a 4-week washout period. Exercise tests, performed after each treatment period while the patients were taking their usual antianginal drugs showed no differences; thus, short-term estrogen does not improve exercise-induced ischemia compared with placebo.
doi_str_mv 10.1016/S0002-9149(96)00685-6
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Aged
Biological and medical sciences
Cardiovascular disease
Coronary Disease - drug therapy
Coronary Disease - physiopathology
Coronary vessels
Cross-Over Studies
Drug therapy
Estradiol Congeners - pharmacology
Estrogen Replacement Therapy
Exercise
Exercise - physiology
Female
Heart - drug effects
Hormones
Hormones. Endocrine system
Humans
Medical sciences
Menopause
Middle Aged
Pharmacology. Drug treatments
Postmenopause
Women
title Estrogen Replacement Therapy and Exercise Performance in Postmenopausal Women With Coronary Artery Disease
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