Estrogen Replacement Therapy and Exercise Performance in Postmenopausal Women With Coronary Artery Disease
We treated 10 postmenopausal women with stable angina, positive exercise test, and documented coronary artery disease with oral conjugated equine estrogen (0.625 mg/day of Premarin) or placebo for 4 weeks, in random order, with crossover after a 4-week washout period. Exercise tests, performed after...
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Veröffentlicht in: | The American journal of cardiology 1997-01, Vol.79 (1), p.87-89 |
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creator | Sbarouni, Eftihia Kyriakides, Zenon S Nikolaou, Nikolaos Kremastinos, Dimitrios Th |
description | We treated 10 postmenopausal women with stable angina, positive exercise test, and documented coronary artery disease with oral conjugated equine estrogen (0.625 mg/day of Premarin) or placebo for 4 weeks, in random order, with crossover after a 4-week washout period. Exercise tests, performed after each treatment period while the patients were taking their usual antianginal drugs showed no differences; thus, short-term estrogen does not improve exercise-induced ischemia compared with placebo. |
doi_str_mv | 10.1016/S0002-9149(96)00685-6 |
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Exercise tests, performed after each treatment period while the patients were taking their usual antianginal drugs showed no differences; thus, short-term estrogen does not improve exercise-induced ischemia compared with placebo.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/S0002-9149(96)00685-6</identifier><identifier>PMID: 9024746</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aged ; Biological and medical sciences ; Cardiovascular disease ; Coronary Disease - drug therapy ; Coronary Disease - physiopathology ; Coronary vessels ; Cross-Over Studies ; Drug therapy ; Estradiol Congeners - pharmacology ; Estrogen Replacement Therapy ; Exercise ; Exercise - physiology ; Female ; Heart - drug effects ; Hormones ; Hormones. Endocrine system ; Humans ; Medical sciences ; Menopause ; Middle Aged ; Pharmacology. 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Exercise tests, performed after each treatment period while the patients were taking their usual antianginal drugs showed no differences; thus, short-term estrogen does not improve exercise-induced ischemia compared with placebo.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Cardiovascular disease</subject><subject>Coronary Disease - drug therapy</subject><subject>Coronary Disease - physiopathology</subject><subject>Coronary vessels</subject><subject>Cross-Over Studies</subject><subject>Drug therapy</subject><subject>Estradiol Congeners - pharmacology</subject><subject>Estrogen Replacement Therapy</subject><subject>Exercise</subject><subject>Exercise - physiology</subject><subject>Female</subject><subject>Heart - drug effects</subject><subject>Hormones</subject><subject>Hormones. 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source | MEDLINE; Elsevier ScienceDirect Journals |
subjects | Aged Biological and medical sciences Cardiovascular disease Coronary Disease - drug therapy Coronary Disease - physiopathology Coronary vessels Cross-Over Studies Drug therapy Estradiol Congeners - pharmacology Estrogen Replacement Therapy Exercise Exercise - physiology Female Heart - drug effects Hormones Hormones. Endocrine system Humans Medical sciences Menopause Middle Aged Pharmacology. Drug treatments Postmenopause Women |
title | Estrogen Replacement Therapy and Exercise Performance in Postmenopausal Women With Coronary Artery Disease |
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