Analysis of loss of heterozygosity and KRAS2 mutations in ovarian neoplasms: Clinicopathological correlations

The molecular events that give rise to ovarian epithelial neoplasms are not well understood. In particular, it is not known whether adenocarcinomas arise from benign or low malignant potential (LMP) precursors. We have examined a large series of benign (25) and LMP (31) ovarian tumors for loss of he...

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Veröffentlicht in:	Genes chromosomes & cancer 1997-02, Vol.18 (2), p.75-83
Hauptverfasser:	Chenevix-Trench, Georgia, Kerr, Judith, Hurst, Terry, Shih, Yang-Chia, Purdie, David, Bergman, Lee, Friedlander, Michael, Sanderson, Barbara, Zournazi, Anna, Coombs, Tania, Leary, Jennifer A., Crawford, Eric, Shelling, Andrew N., Cooke, Inez, Ganesan, Trivadi S., Searle, Jeffrey, Choi, Chan, Barrett, J. Carl, Khoo, Soo-Keat, Ward, Bruce
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosome Deletion Female Genes, ras Heterozygote Humans Mutation Neoplasm Staging Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology Survival Analysis
Online-Zugang:	Volltext
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